Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic disease of the liver, presumably autoimmune in nature, that leads to progressive cholestasis through intrahepatic bile duct destruction [1] and often end-stage liver disease (see the image below). The name...
Initially primary sclerosing cholangitis may be asymptomatic if the flow of bile is not significantly impeded. This asymptomatic phase can be as long as 10 years in some cases. Gradually symptoms become apparent. However, at the outset the symptoms may be vague and not attributed to the biliary...
Primary biliary cholangitis(PBC) is a chronic autoimmune disease of the liver that is characterized by progressive cholestasis and inflammation due to destruction of the intrahepatic bile ducts. If left untreated, it can lead tocirrhosis and liver failure.PBCis thought to be the result of a combin...
increasing liver tests, bacterial cholangitis, or other signs of clinical decompensation. When a dominant biliary stricture of the common bile duct, common hepatic duct, or intrahepatic duct is identified, the potential diagnosis of cholangiocarcinoma should be considered.[31]Cholangiocarcinoma...