PPAR signaling pathway overview Like other nuclear receptor super families, PPAR is essentially a class of ligand-dependent transcriptional regulators, all of which are single subunits with an N-terminal region (A/B region), a highly conserved DNA-binding region (C region), and the hormone ...
登录 注册 待分类 > 待分类 > 细胞信号-PPAR Signaling Pathway 下载文档 收藏 打印 转格式 525阅读文档大小:65.65K1页abas上传于2011-07-10格式:JPG
各差异基因的表达量变化见表2。 表2分化不同时间PPAR信号通路的差异表达基因变化Table 2Changes of differentially expressed gene in PPAR signaling pathway at different differentiation time 3讨论 脂肪酸是机体主要能量来源之一,通过核受...
Theocharis, "PPAR-γ signaling pathway in placental development and function: a potential therapeutic target in the treatment of gestational diseases," Expert Opinion on Therapeutic Targets, vol. 12, no. 8, pp. 1049-1063, 2008.Giaginis C, Spanopoulou E, Theocharis S. PPAR-gamma signaling ...
The PPAR signaling pathway plays an essential role in trophoblastic cell fusion, migration, angiogenesis, lipid metabolism, and trophoblastic cell cycle progression, and its overactivation suggests complex biological functions, including placental immune tolerance, trophoblastic cell invasion, syncytium ...
and chemokine-chemokine receptor interaction were significantly enriched in the AI lesions. GSEA demonstrated that the PPAR signaling pathway was significantly weakened in the AI lesions. The mRNA expression levels of PPARA and PPARG were significantly lower in the AI patients (0.336 ± 0.120, 0.253 ...
PPAR signaling pathway may be an important predictor of breast cancer response to neoadjuvant chemotherapy. PPAR signaling pathway may be an important predictor of breast cancer response to neoadjuvant chemotherapy[J]. Cancer Chemother Pharmacol, 2012, 70(5): ... YZ Chen,JY Xue,CM Chen,... -...
Abstract:Objective To explore the role of the PPARα/HOXA10 signaling pathway in mediating the effect of adiponectin (APN) for improving endometrial receptivity in a rat model of polycystic ovary syndrome (PCOS). Methods Forty female SD rat models with letrozole-induced PCOS were randomized, with...
10. Li Y, Yuan L, Jiang S, Liu S, Xia L, Shen H, et al. Interleukin-35 stimulates tumor necrosis factor-α activated osteoblasts differentiation through Wnt/β-catenin signaling pathway in rheumatoid arthritis. Int ...
Ameliorative Effect of Ethanolic Echinacea purpurea against Hyperthyroidism-Induced Oxidative Stress via AMRK and PPAR Signal Pathway Using Transcriptomics and Network Pharmacology Analysis Echinacea purpurea (L.) Moench (EP) is a well-known botanical supplement with antioxidant characteristics. However, the...