PPAR signaling pathway PPAR signaling pathway Cascade The PPARγ-related signal transduction pathways include the following: 1. PPARγ activation pathway. PPARγ binds directly to the ligand; ligand regulates P
登录 注册 待分类 > 待分类 > 细胞信号-PPAR Signaling Pathway 下载文档 收藏 打印 转格式 531阅读文档大小:65.65K1页abas上传于2011-07-10格式:JPG
PPAR signaling pathway Placenta Trophoblast In vitro fertilization and embryo transfer (IVF-ET) In first trimester Adverse perinatal outcomes 1. Introduction Assisted reproductive technology (ART) is described as a series of medical treatments used to achieve a successful pregnancy, in which both oocytes...
3.4. STX-0119 modulates chondrocyte anabolic and catabolic metabolism through regulation of the STAT3/PPARγ signaling pathway Quantitative PCR and Western blot analysis revealed that STX-0119 inhibited the phosphorylation of STAT3 at the protein level in a concentration-dependent manner (Fig. 4A, B)...
( mTOR ) signalingpathwayinhyperuricemiaGinducedpancreaticcellapoptosis. Methods HyperuricemicuricaseGknockout ( SCDGKO ) andcontrolwildGtype ( SCDGWT ) malemicewerefedastandardchowdiet.Theglucosetolerancetest ( GTT ) wasperformedat18weeks.At20weeks , theinsulinresistancetestwasperGformed ; thelevelsof...
This suggests that EE, at least in part, ameliorates sevoflurane-induced learning and memory impairment through the PPARγ signaling pathway. 2. Methods and Materials 2.1. Animals Anesthesia and Treatment Six-day-old C57/BL wild-type male mice were obtained from the specific pathogen-free animal ...
The fuction of PPARγ signaling pathway in modulating carcinogenesis is controversial. Methods: The expression of PPARγ and association with overall survival were analyzed in patients from two cohorts. The effect of PPARγ activation on cell proliferation, cell cycle, and cell apoptosis were ...
Taken together, our results prove that melatonin treatment modulated inflammation and BBB disruption and improved cognitive function in VaD rats, partly by activating the SIRT1/PGC-1α/PPARγ signaling pathway. This is a preview of subscription content, log in via an institution to check access. ...
However, the significance of PPARγ-CD36 signaling pathway in the detrimental effect of atypical antipsychotic drugs on atherosclerosis is limited. Given the impact of atypical antipsychotic agents in the pathogenesis of metabolic diseases, we aimed to characterize the molecular mechanisms of atypical ...