Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts. Am J Physiol Heart Circ Physiol 2003;285:H2373 -H2381.Gupta RC, Mishra S, Rastogi S, Imai M, Habib O, Sabbah HN. Cardiac SR-coupled PP1 activity and expression...
数据来源文献 [1]. Hanke JH, et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem. 1996 Jan 12;271(2):695-701. 规格 10mg 20mg 50mg PP1 是一种有效的选择性 Src 家族抑制剂。此...
图1.Okadaic acid（冈田酸）化学结构 Okadaic acid（冈田酸）基础信息 中文名：黑海棉酸;冈田酸;英文别名：Okadaic acid;PP1 and PP2A inhibitor； PP2A inhibitor； PP1inhibitor CAS号：78111-17-8 结构式：：CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(...
目前,研究人员已经初步了解到 PP1 介导的 Akt 去磷酸化作用是通过 PP1 磷酸酯酶亚基(PPP1R1B,也称为 Inhibitor-1)和 Akt 相互作用实现的。在无 Stim1 过程中,PP1 磷酸酯酶亚基能够与 Akt 亚基相互结合,这一作用能够促进 PP1 选择性地去磷酸化 Akt 的 Ser473 残基,从而抑制 Akt 的活性。同时,PP1 的...
MeV interacts with the DC-SING receptor leading to the activation of Raf-1 kinase. Raf1 phosphorylate inhibitor 1 (I-1), a potent PP1 inhibitor, avoids RIG-I/MDA5 activation. In late MeV infection, protein V prevents MDA5 dephosphorylation by acting as a PP1-substrate. In α-CoV infect...
2、1. T.U. Marron, et al. Preliminary safety, pharmacokinetics and immunomodulatory activity of RBS2418, an oral ENPP1 inhibitor, alone and in combination with pembrolizumab in patients with solid tumors. 1025MO. 药渡媒体商务合作...
PP1 (Src Inhibitor) 供应商 Cayman Chemical 产品货号 14244-1 产品报价 ￥询价/1mg 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 产品新闻 背景资料 Cayman Chemical是生化小分子标准品专家,艾美捷作为中国区域总代理,提供Cayman Chemical原装进...
英文别名:1-(1,1-Dimethylethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;1-tert-Butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine;1-tert-Butyl-3-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine;AGL 1872;EI 275;PP 1;PP 1 (enzyme inhibitor); ...
In addition, glucose-induced insulin secretion was inhibited by nuclear inhibitor of PP-1 and calyculin A, which was in part mediated by a reduction of PP-1-dependent calcium influx into INS-1 β-cells. These results identify a novel molecular pathway by which leptin confers inhibitory action ...
PP1 (Src Inhibitor) 供应商 Cayman Chemical 产品货号 14244-5 产品报价 ￥询价/5mg 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 产品新闻 背景资料 Cayman Chemical是生化小分子标准品专家,艾美捷作为中国区域总代理,提供Cayman Chemical原装进...