Post-transcriptional modification is a process in cell biology by which, in eukaryotic cells, primary transcript RNA is converted into mature RNA. A notable example is the conversion of precursor messenger RNA into mature messenger RNA (mRNA), which includes splicing and occurs prior to protein ...
post-transcriptional modification名词解释1.转录2.不对称转录3.模板链4.编码链5.启动子6.断裂基因7.外显子8.内含子9.剪接体1
It remains unclear, however, which mechanisms of miRNA production or modification are organ-specific and the extent of their evolutionary conservation. To address these issues, we developed the software(PRocessing Of Short Transcripts), which, among other features, helps quantify mature miRNAs, ...
Post-transcriptional modification refers to the process of altering RNA molecules after transcription, playing a crucial role in various biological processes. AI generated definition based on: Methods in Enzymology, 2015 About this pageSet alert
Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells. Oncogene 2017, 36, 4732-4738. [CrossRef] [PubMed]Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells. MOTZIK A,AMIR ...
转录后的加工（posttranscriptionalmodification）（1）减少部分片段：如切除5′端前导序列，3′端拖尾序列和中部的内含子；（2）增加部分片段：5′加帽，3′加poly(A)，归巢和通过编辑加入一些碱基；（3）修饰：对某些碱基进行甲基化等。转录后加工转录后的加工（posttranscriptionalmodification）第一节tRNA和rRNA的...
B)Covalentmodification: AddacapandapolyAtailtomRNA Addamethylgroupto2’-OHofriboseinmRNAandrRNA ExtensivechangesofbasesintRNA C)Splicing pre-rRNA,pre-mRNA,pre-tRNAbydifferentmechanisms. TheLongandWinding Road….. EukaryoticandProkaryoticmRNAs HaveMajorDifferences-I ...
The first is mRNA processing or post-transcriptional modification . It occurs between transcription and translation in eukaryotes, but does not occur in bacteria. The process involves a series of modifications that the RNA transcript (hnRNA) must undergo before it can be translated (Fig. 5.1). ...
Although modifications play essential roles in tRNA biology, methods to directly detect their introduction during tRNA maturation are rare and do not easily provide information on the temporality of modification events. To obtain information on the tRNA maturation process, we have developed a methodology...
Post-transcriptional modification genes RBM10 (3.16%, 11/348) and METTL14 (0.86%, 3/348) act as well-known alternative splicing regulators and m6A writers. Importantly, we identified recurrent mutations in METTL14, and all mutations in this gene affected the same amino acid (Supplementary Fig....