转录后加工转录后的加工(posttranscriptionalmodification)第十三章转录后加工 转录后的加工（posttranscriptionalmodification）（1）减少部分片段：如切除5′端前导序列，3′端拖尾序列和中部的内含子；（2）增加部分片段：5′加帽，3′加poly(A)，归巢和通过编辑加入一些碱基；（3）修饰：对某些碱基进行甲基化等。转录...
Post-transcriptional modification is a process in cell biology by which, in eukaryotic cells, primary transcript RNA is converted into mature RNA. A notable example is the conversion of precursor messenger RNA into mature messenger RNA (mRNA), which includes splicing and occurs prior to protein ...
modificationrrnatrnarna间隔区genes RNAPosttranscriptional Procession 转录后加工 ClassesofRNA •Pre-RNA,前体RNA:Theprimarytranscripthasthesame organizationasthegene •hnRNA,heterogeneousnuclearRNA,核内不均一RNA:Eucaryotic RNAPolIItranscribesavarietyofdifferentgenes •snRNA,smallnuclearRNA,核内小RNA:isanyone...
Post-translational modification generally refers to the addition of a functional group covalently to a protein as in phosphorylation and neddylation, but also refers to proteolytic processing and folding processes necessary for a protein to mature functionally. Featured Epigenetic modification increases ...
Post-transcriptional modification refers to the process of altering RNA molecules after transcription, playing a crucial role in various biological processes. AI generated definition based on: Methods in Enzymology, 2015 About this pageSet alert Also in subject area: Biochemistry, Genetics and Molecular...
位 RNA-Pol 真核生物的转录后修饰 Post-transcriptional Modification ... www.docstoc.com|基于2个网页 3. 转录后加工 转录后加工(post-transcriptional modification) 转录后加工( )( post-transcriptional processing): ) 是指将各种前体R…wenku.baidu.com|基于1 个网页...
Quality control of a transcriptional regulator by SUMO-targeted degradation. Mol Cell Biol. 2009;29:1694–706. Article PubMed PubMed Central Google Scholar Yuan H, Han Y, Wang X, Li N, Liu Q, Yin Y, et al. SETD2 restricts prostate cancer metastasis by integrating EZH2 and AMPK ...
Indeed, chromatin modification dynamic changes were imposed by an ability or inability to maintain equilibrium in the opposing effects of methylases and demethylases. The simultaneous removal of one histone methylation mark and an addition of another enable transcriptional tuning [99, 100]. Nonhistone ...
(TF)analysis.Thesemodificationsoccurinthemajorityofproteinsinvolvedin transcriptionalregulation,includingtranscriptionfactors,coactivators,repres- sors,generaltranscriptionfactors,histones,andRNApolymerases.Protein phosphorylationisprobablythemoststudiedposttranslationalmodification. Interestingly,phosphorylationhasbeendemonstratedto...
Phosphorylation of pRb regulates its pro-apoptosis or pro-survival functions in a cell cycle-independent fashion. On one hand, site-specific pRb phosphorylation sequesters pRb from E2F, increases E2F transcriptional activities and triggers cell death. For example, CDK4/6-mediated phosphorylation of pR...