Most anti-proliferative signals depend on the activity of which protein? What post-translational modification is involved in controlling the activity of this protein? Describe three distinct molecular mechanisms whereby the signaling circuit that governs ...
(post-transcriptional modification) before translation. ncRNAs are classified into two groups: short ncRNAs and long ncRNAs. Both ncRNA groups function in manipulating protein production of other genes by controlling heterochromatin formation, histone modification, DNA methylation or acetylation, and mRNA ...
Acetylation modification is a highly conserved and reversible protein modification in the body, which plays a very important role in the activation of transcriptional regulatory factors in the nucleus. In addition, there are a large number of non-histone acetylation modifications involved in the regulat...
This PTM is active at the level of transcription, post-transcriptional, post translational cellular activity, and cellular signaling in several immune cell types, including neutrophils, B cells, T cells, natural killer cells, macrophages, and lymphoid or myeloid cancer cells. Of interest, O-...
heavy metals; transcriptional; posttranscriptional. Cytochrome P450 constitutes a major family of xenobiotic metabolizing enzymes which transform xenobiotics to nontoxic or carcinogenic metabolites (=-=Guengerich, 2004-=-). The cytochrome P450 1a1 (Cyp1a1) is of major interest because of its role in...
A fundamental question in biology is how genome-wide changes in gene expression are enacted in response to a finite stimulus. Recent studies have mapped ch... Sarah,Franklin,Haodong,... - 《Molecular & Cellular Proteomics Mcp》 被引量: 41发表: 2012年 Transcriptional transgene silencing and chro...
Is transcriptional regulation just going through a phase? Mol Cell, 81 (2021), pp. 1579-1585 View PDFView articleView in ScopusGoogle Scholar 108 G. Arya, T. Schlick Role of histone tails in chromatin folding revealed by a mesoscopic oligonucleosome model Proc Natl Acad Sci U S A, 103 ...
Endogenous mRNA molecules undergo post-transcriptional modifications, including 5'-capping and polyadenylation, for the stability of mRNA and efficient translation. Naturally, 7-methylguanosine cap (m7G) is added to the first nucleotide of a mRNA chain via 5' to 5' linkage. The 2'-OH of the ri...
What is the process by which mRNA is decoded and a protein is produced? Describe the steps of making an mRNA from a pre-mRNA. What is mRNA processing? Explain the process of post-transcriptional modification specifically at the 5' end of the mRNA. ...
What is the function of the feather type calamus? What is a ribozyme? What is an osmoregulator? What types of water pollution exist? Select one type and discuss its effects on the environment and biodiversity. What are the types of post-translational modification?