Acetylation modification is a highly conserved and reversible protein modification in the body, which plays a very important role in the activation of transcriptional regulatory factors in the nucleus. In addition, there are a large number of non-histone acetylation modifications involved in the regulat...
Explain the process of post-transcriptional modification specifically at the 5' end of the mRNA. What is a sequence of mRNA that codes for an amino acid called? Once mRNA is created through transcription, it ...
Post-translational modification by the ubiquitin-like SUMO protein is emerging as a defining feature of eukaryotic cells. Sumoylation has crucial roles in ... JS Seeler,A Dejean - 《Nature Reviews Molecular Cell Biology》 被引量: 1297发表: 2003年 Ubiquitin-binding domains Ubiquitin-binding domains...
This PTM is active at the level of transcription, post-transcriptional, post translational cellular activity, and cellular signaling in several immune cell types, including neutrophils, B cells, T cells, natural killer cells, macrophages, and lymphoid or myeloid cancer cells. Of interest, O-...
m6A modification is considered the most prevalent RNA modification in mammalian cells, emerging in both coding RNAs and non-coding RNAs [1–5]. This epi-transcriptional modification is known to promote the initiation and progression of many human diseases [6–8]. As is widely understood, m6A mo...
What is the process by which mRNA is decoded and a protein is produced? Describe the steps of making an mRNA from a pre-mRNA. What is mRNA processing? Explain the process of post-transcriptional modification specifically at the 5' end of the mRNA. ...
Is transcriptional regulation just going through a phase? Mol Cell, 81 (2021), pp. 1579-1585 View PDFView articleView in ScopusGoogle Scholar 108 G. Arya, T. Schlick Role of histone tails in chromatin folding revealed by a mesoscopic oligonucleosome model Proc Natl Acad Sci U S A, 103 ...
Post-translational modificationKATHDACDNA methylationAmeliorationHD is a paradigm of altered epigenetics in neurodegenerative disorders.Epigenetic-based therapies are beneficial in HD models.The relationship between epigenetic and transcriptional dysregulation is unclear.Additional factors and processes sh...
What is an osmoconformer? What are biopolymers? What is a kinetochore? What is Lamarckism? What is the neuropithelia? What are the different types of fermentation? (a) What is parasitoid? (b) What is hyperparasitoid? What are the types of post-translational modification?
A short overview of the major biochemical reactions focusing on the flavonol and anthocyanin branch of flavonoid biosynthesis (FB) in Arabidopsis thaliana is provided in Fig. 1. The different branches of the pathway are strongly activated on the transcriptional level as part of the high light (...