post-translational modifications (PTMs), including acetylation, methylation, phosphorylation and ubiquitination (mainly in N-terminal) The histone code hypothesis : specific PTMs regulate gene expression by two mechanisms: (1) changing the chromatin structure into activated or repressed transcriptional ...
转录后加工转录后的加工(posttranscriptionalmodification)第十三章转录后加工 转录后的加工（posttranscriptionalmodification）（1）减少部分片段：如切除5′端前导序列，3′端拖尾序列和中部的内含子；（2）增加部分片段：5′加帽，3′加poly(A)，归巢和通过编辑加入一些碱基；（3）修饰：对某些碱基进行甲基化等。转录...
(TF)analysis.Thesemodificationsoccurinthemajorityofproteinsinvolvedin transcriptionalregulation,includingtranscriptionfactors,coactivators,repres- sors,generaltranscriptionfactors,histones,andRNApolymerases.Protein phosphorylationisprobablythemoststudiedposttranslationalmodification. Interestingly,phosphorylationhasbeendemonstratedto...
Post-transcriptional modification is a process in cell biology by which, in eukaryotic cells, primary transcript RNA is converted into mature RNA. A notable example is the conversion of precursor messenger RNA into mature messenger RNA (mRNA), which includes splicing and occurs prior to protein ...
Post-transcriptional modification refers to the process of altering RNA molecules after transcription, playing a crucial role in various biological processes. AI generated definition based on: Methods in Enzymology, 2015 About this pageSet alert Also in subject area: Biochemistry, Genetics and Molecular...
post-transcriptional modification名词解释1.转录2.不对称转录3.模板链4.编码链5.启动子6.断裂基因7.外显子8.内含子9.剪接体1
位 RNA-Pol 真核生物的转录后修饰 Post-transcriptional Modification ... www.docstoc.com|基于2个网页 3. 转录后加工 转录后加工(post-transcriptional modification) 转录后加工( )( post-transcriptional processing): ) 是指将各种前体R…wenku.baidu.com|基于1 个网页...
Learning Outcomes Describe RNA post-transcriptional modification and its purpose Gene expression can be regulated at various stages after an RNA transcript has been produced. Some transcripts can undergoalternative splicing. This regulated process makes different mRNAs and proteins from the same initial RNA...
modificationrrnatrnarna间隔区genes RNAPosttranscriptional Procession 转录后加工 ClassesofRNA •Pre-RNA,前体RNA:Theprimarytranscripthasthesame organizationasthegene •hnRNA,heterogeneousnuclearRNA,核内不均一RNA:Eucaryotic RNAPolIItranscribesavarietyofdifferentgenes •snRNA,smallnuclearRNA,核内小RNA:isanyone...
Furthermore, Sox6 sumoylation of either Lys404 (hs/mm) and Lys417 (hs/mm) perturbs its transcriptional activity [57]. Disruption of the SUMO modification site or its conjugating enzyme, Ubc9, result in an increase in transcriptional activity in both Sox2 and Sox6 [56,57]. Ubc9 has ...