Post-translational modifications are modifications that occur on a protein, catalysed by enzymes, after its translation by ribosomes is complete. Post-translational modification generally refers to the addition of a functional group covalently to a protein as in phosphorylation and neddylation, but also...
Part of the maturation process of small RNAs are post-transcriptional modifications either on the ribose or base moiety of the nucleotide. Additionally, deletion and/or addition of nucleotides by RNA-specific ribonucleotidyl transferases are also plausible (RNA 13:1834–1849, 2007). In this ...
The Genetic Code is arranged into sixteen codon boxes, where the four codons in each box are similar in their first two letters but differ at the third position (the wobble position). In the universal Genetic Code, each amino acid, except for Tryptophan and Methionine that have one codon ea...
Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function 翻译后修饰在调节c-Myc蛋白水解、转录活性和生物学功能中的作用 相关领域 磷酸化 癌变 蛋白质水解 生物 细胞生物学 泛素 转录调控 功能(生物学) 细胞周期 细胞凋亡 转录因子 基因 遗传学 ...
He, Post-transcriptional gene regulation by mRNA ... BS Zhao,IA Roundtree,C He - 《Nature Reviews Molecular Cell Biology》 被引量: 0发表: 2018年 Faculty Opinions recommendation of Post-transcriptional gene regulation by mRNA modifications. He, Post-transcriptional gene regulation by mRNA ...
Posttranscriptional modifications on the base or sugar of ribonucleosides generally result in mass increases that can be measured by mass spectrometry. Mat... S Douthwaite,F Kirpekar - 《Methods in Enzymology》 被引量: 117发表: 2007年 Advancement in the routine identification of anaerobic bacteria...
Post-translational modifications (PTMs) include a collection of add-ons that provide variability to a defined set of proteins that all cells use to enable most biological processes, adapting the functionality of those proteins by varying their interactive capability, resistance to degradation, etc. In...
Hann SR. Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function. Semin Cancer Biol. 2006; 16:288-302.Hann SR. Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function....
Protein acetylation not only plays a role in chromosome structure and activation of transcriptional regulators in the nucleus but also under physiological conditions, and a large number of non-nuclear proteins are acetylated. Acetylation is ubiquitous in cell metabolism, the cell cycle, cell signaling ...
Protein acetylation not only plays a role in chromosome structure and activation of transcriptional regulators in the nucleus but also under physiological conditions, and a large number of non-nuclear proteins are acetylated. Acetylation is ubiquitous in cell metabolism, the cell cycle, cell signaling ...