ANA IIF is an effective screening assay in patients with clinical features of SLE and will detect most anti-ssDNA, anti-dsDNA, ENAs, and other autoantibodi... W Egner - 《Journal of Clinical Pathology》 被引量: 626发表: 2000年 Report of a False-Positive HIV Test Result and the Potential...
Although the 2019 EULAR/ACR classification criteria for systemic lupus erythematosus (SLE) has required at least a positive anti-nuclear antibody (ANA) titer (≥ 1:80), it remains challenging for clinicians to identify patients with SLE. This study ai
The laboratory data included various markers, including IL-1β, IL-6, IL-10, TNF-α, CRP, the neutrophil-to-lymphocyte ratio (NLR), C3, C4, IgG, and anti-dsDNA antibodies. Disease severity among AQP4-IgG-positive NMOSD patients was assessed via EDSS scores [27]. In previous studies, ...
Rapid progressive interstitial lung disease (RP-ILD) is the leading cause of anti-melanoma differentiation associated protein 5 antibody positive dermatomyositis (anti-MDA5+DM) related death. Elevated serum B-cell activating factor (BAFF) levels have been implicated in connective tissue diseases associat...
The most commonly ordered tests were antinuclear antibody (ANA), anti-double-stranded DNA (dsDNA) antibody, and rheumatoid factor (RF). Of the 89% (83/93) who...doi:10.1186/1546-0096-8-27Peter N MallesonMurray J MackinnonMichaela Sailer-Hoeck...
Cells resuspended by PBS were incubated by Alexa Fluor 488 anti-human EGFR (5ul/test; BioLegend, #352908, lot: B332782) for 15 minutes at room temperature. Alexa Fluor 488 Mouse IgG1, κ Isotype Ctrl (FC) Antibody (5ul/test; BioLegend, #400129, lot: B354284) were used as ...
(Fig.4c); The dsDNA (Mann Whitney two-tailed testp < 0.000) and ssRNA (Mann Whitney two-tailed testp < 0.000) NGSRe-normwere elevated in the HC plasma compared to DM, whereas no significant change was observed in ssDNA viruses (Unpairedttestp:0.19) or RNA reverse-transcribing ...
To study the significance of ANA(antinuclear antibody),ENA(antibody to extractable nuclear antigent),ds-DNA(anti-dsDNA antibody)andANCA(antineutrophil cytoplasmic antibody) in the diagnose,monitoring and therapy of SLE. 探讨抗核抗体 (ANA)、抗盐水可提取性抗原多肽抗体谱 (ENA)、抗双链DNA抗体 (DSD ...
Abstract Antinuclear antibodies (ANAs) are a serological hallmark of systemic autoimmune rheumatic diseases (SARDs); however, few studies have investigated their post-treatment levels. The mechanism by which ANA titers are upregulated in SARDs remains unclear. We assessed factors associated with the ANA...
Taken together, these data indicate that the efficiency of NHEJ, but not of HR, is negatively affected by anti-estrogen therapy in ER+ models of breast cancer and may be contributing to the radiosensitization phenotype observed with concurrent administration of anti-estrogen therapy and RT. Cell...