Identification of sFlt1 polyA signal sequences and mapping intronic cis-elements that regulate sFlt1 in human placentaDoSDDoSDGT (Directed Geographical tracebackIP tracebackSDR (Segment Direction RatioThe article offers information on the Internet Protocol (IP) traceback solutions and direction ration ...
我们结合相关研究进展和自身工作基础,涉及并合成了不同长度的polyA RNA分子,依靠脂质体转染入细胞中,得到了polyA RNA分子在外源基因表达调控相关信息,并实施于抑制外源基因表达的应用中。 [0017] The term “polyA” as used herein, refers to a signal sequence which causes cleavage at a specific site at the...
SV40 PolyA(猴空泡病毒PolyA, 简称PolyA)序列是有转录终止作用和使转录的mRNA 添加PolyA 尾的 DNA 序列(240 bp), 含有AATAAA 六核苷酸多腺苷化信号(Polyadenylation signal)。 AATAAA六核苷酸是最早被认识到的mRNA多腺苷化信号[1], 90%的真核mRNA 的AATAAA 序列都在距剪切位点的30 个核苷酸的范围内[2], 它指导...
多腺苷化信号又称PolyA信号(Polyadenylationsignal), AAUAAA(在基因组序列中表示为AAl’AAA)是其主要形式, 参与真核mRNA 3’端形成的重要过程。己知Alu序列和PolyA 信号与多种生物学现象关联,如Alu的插入或缺失可引起肿 瘤、染色体重组等;而一大类导致地中海贫血的血红蛋白病 都归因于AAUA八A这个序列的点突变。本...
A thalassemia caused by a polyadenylation signal mutation. Nature This idea is strengthened by observations on the effect of deletion mutations in or around the AATAAA sequence on polyadenylation of late simian virus 40 (SV40) mRNA; removal of this sequence prevents poly(A) addition. Naturally .....
英文缩写 英文缩写 LINEs longinterspersed nuclearelements SINEs short interspersed nuclearelements LTR long terminal repeat UTR untranslatingregion ORF openreading frame EGFP enhanced green fluorescent protein SV40 simianvirus40 PolyA polyadenylationsignal NS nornlalsaline SDS sodium dodecylsulphate PBS phosphate...
这一过程需要pre—mRNA中有信号序列的存在,他们是 多聚腺苷化信号序列(polyadenylation signal sequence),如5AAUAAA3’, AAU儿蚣是出现在pre-mRNA的3’端附近的信号。常见的poly(A)信号有AAUAA、 AUUAAA、UAUAAA、AGUAAA、GAUAAA、CAUAAA、AAUAUA、AAUACA、 AAUGAA、AAUAGA、AACAAA、ACUAAA、UUUAA【11 J。在...
Here we report on the design of a splicing based lentiviral platform that combines a polII promoter for minimized toxicity and cell specific expression, shRNAs derived from intron based pre-microRNA, exon based protein expression, a modified polyA signal for minimal downstream effects and 3rd ...
关键词: Alu; SV40 PolyA; AATAAA 信号; GFP; 转录终止 The effects of SV40 PolyA sequence and its AATAAA signal on up-stream GFP gene expression and transcription termination LI Shu-Ping 1, 2 , FENG Jing-Jing 3 , WANG Hong-Gang 4 , WANG Xiu-Fang 1 , LV Zhan-Jun 1 1. Department of...
【化】 聚腺苷酸 分类: 化学化工|查看相关文献(pubmed)|免费全文文献 详细解释: 以下为句子列表: 英文: The effects of SV40 PolyA sequence and its AATAAA signal on upstream GFP gene expression and transcription termination 中文: SV40 PolyA序列及其AATAAA信号对上游GFP基因表达及转录终止的影响更详细... ...