第5版WHO造血与淋巴组织肿瘤分类尚未完整发表,根据介绍文献,这一版中命名为Acute promyelocytic leukaemia(APL)with PML::RARA fusion,用::取代了-。 第3版、第4版和修订第4版WHO造血与淋巴组织肿瘤分类是美国血液病理学会(SH)、欧洲血液病理协会与血液病理学会学会(EAHP)与世界卫生组织/国际癌症研究机构(WHO/IRAC...
PML/RARA 融合基因检测试剂盒(荧光原位杂交法)说明书 【产品名称】 通用名:PML/RARA 融合基因检测试剂盒(荧光原位杂交法) 英文名:PML/RARAFusion Detection Kit (Fluorescent in situ Hybridization Method) 【包装规格】20 人份/盒. 【预期用途】 本试剂盒适用于定性检测白血病患者骨髓样本中的PML/RARA 融合基因,...
PML(E6)-RARA(E3) FusionEnquiry Product Description Product database CBP20205R FormatRNA DescriptionPML, PML nuclear body scaffold, also known as promyelocytic leukemia is a nuclear phosphoprotein that is associated with cellular functions related to cell adhesion, differentiation, migration, and prolifera...
名称L_PML(E6)-RARA(E3) Fusion 型号CBP20205R 报价 特点L_PML(E6)-RARA(E3) Fusion 详细内容 CBP20205R FormatRNA DescriptionPML, PML nuclear body scaffold, also known as promyelocytic leukemia is a nuclear phosphoprotein that is associated with cellular functions related to cell adhesion, differentia...
(二)急性白血病(AL)伴变异型RARA易位 A subset of cases, often with morphological features resembling those of APL, show variant translocations involving RARA. The variant fusion partners include ZBTB16 (previously called PLZF) at 11q23.2, ...
ObjectiveTo construct, express, and purify the prokaryotic expression vector for PML-RARα fusion gene related proteins. MethodsPML-RARα-pET32a(+) plasmid was used as a template and 1 200 bp sequences of PML and RARα were amplified by polymerase chain reaction and subcloned into expression ...
关键词 微滴式数字PCR;急性早幼粒细胞白血病;外泌体;PML-RARA融合基因中图分类号R733.1;R446.1 文献标识码Adoi:10.197461j.cnki.issnl009—2137.2019.03.017Detection of Exosomal PML.RARA Fusion Gene Expression Levelby Droplet Digital PCRZHU Hui“2,wAⅣG Zhe—Yin92,D,^^G Xiao—Qing。乞WANG Rui-...
ConclusionsThe clinical characteristics of different PML-RARα fusion gene isoforms are different, including most-common L type, more-common V type and S type in high risk groups; complicated RAS is commonly found in S type during the treatment. And different isoforms have no effect on the CR...
内容提示: ·基础研究 · 2 0 0 9年 4月 第 47卷 第1 1期 急 性早幼 粒细胞自 血病PML/ RARa 融合 基因的 检测 杨光 赵瑾 石磊 王恺 : 解菊芬 2 马莉 ( 1. 山西医科大学儿科系; 2. 山两医科大学第二医院血液科; 3. 山西医科大学第二医院风湿科, 太原 030001) 【 摘要】目的 探讨荧光原位...
promyelocytic , acute ; all‐trans‐retinoic acid ; arsenic trioxide ; PML‐RARa fusion gene△, Chen Jianbin , Wang Jianyu , Xiao Qin 急性早幼粒细胞白血病(acute promyelocytic leukemia ,APL)是急性髓系白血病的一个特殊亚型 , 其发病的分子基础是因特异性染色体 t(15;17)易位形成的 PML‐RARa 融合基...