2024 EHA abstract PB2972.EVALUATION OF FERTILITY IN WOMEN TREATED WITH THE R-DA-EPOCH REGIMEN FOR PRIMARY MEDIASTINAL B CELL LYMPHOMA (PMBCL). 声明 公众号及作者不承担相关责任。合作联系邮箱:Htology@edoctor.work。
若中期PET-CT评估提示尚未达到CMR者,可考虑加用BV或PD-1单抗,以争取达到诱导治疗结束后的CMR,进而避免后续的RT巩固,然而该策略亦需前瞻性研究来证实其有效性和安全性。 原文链接:Emanuele Zucca, Andrew Davies, Irina Kryachok, et al...
此外，PMBCL还需要与结节硬化型cHL(nodular sclerosis classical Hodgkin lymphoma，NScHL).和继发纵隔浸润...
MACOPB研究首次评估了PET在指导放疗的作用,仅PET阳性(IHP标准)患者接受放疗,结果10年PFS率与治疗结束时(end of treatment,EOT)PET扫描状态无关,均为90%左右(P=0.85)。 另一项研究(见表3)中,International Extranodal Lymphoma Study Group (IELSG)在R-VACOPB/RMACOPB化疗+放疗巩固后,通过PET扫描评估了治疗结束...
PMBCL(Primary Mediastinal B-cell Lymphoma)是一种罕见的恶性肿瘤,起源于淋巴组织。它通常发生在年轻人身上,尤其是女性。PMBCL的化学结构与其他淋巴瘤不同,这使得它具有独特的临床特征和治疗挑战。 PMBCL的化学结构主要由B细胞克隆所构成。这些克隆细胞在肿瘤组织中形成大块的肿瘤,这些肿瘤通常位于纵隔区域。与其他淋巴瘤...
英文标题:Primary mediastinal B-cell lymphoma have superior outcome compared to diffuse large-B-cell lymphoma treated with Axicabtagene ciloleuce the CART-SIE reallife Italian study 中文标题: Axi-cel治疗PMBCL比DLBCL疗效更优:CART-SIE意大利真实世界研究 ...
原文链接:Emanuele Zucca, Andrew Davies, Irina Kryachok, et al. Observation vs. radiotherapy in primary mediastinal B-cell lymphoma patients with complete response to standard immunochemotherapy: The IELSG37 randomized trial. ASCO 2023 Abstract LBA7505 ...
The FDA's approval of Yescarta is for treatment of patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), the most common type of non-Hodgkin lymphoma, and several more rare types including primary mediastinal large B-cell lymphoma (PMBCL), high-grade B-cell lymphoma, and...
Savage KJ, Yenson PR, Shenkier T, Klasa R, Villa D, Goktepe O, et al. The Outcome of Primary Mediastinal Large B-Cell Lymphoma (PMBCL) in the R-CHOP Treatment Era. ASH Annual Meeting Abstracts. 2012;120(21):303-.Savage KJ, Yenson PR, Shenkier T, Klasa R, Villa D, Goktepe O...
Use of a gene expression-based assay in the molecular classification of large B-cell lymphoma in the mediastinum into PMBCL and DLBCL. By leveraging the wealth of gene expression profiling (GEP) data obtained from PMBCL samples,3,4 the authors sought to establish a molecular assay that would ...