(2004). Properties of pluripotent human embryonic stem cells BG01 and BG02. Stem Cells, 22 , 292–312.Zeng X., Miura T., Luo X., Bhattacharya B., Condie B., Chen J. et al. (2004) Properties of pluripotent human embryonic stem cell BG01 and BG02. Stem Cells 22 , 292–312....
Pluripotent embryonic stem cells (ESCs) are obtained from the inner mass of blastocysts and can be cultured indefinitely in vitro with their stemness properties intact. Following their culture into three-dimensional aggregates called embryoid bodies, ESCs in vitro spontaneously differentiate into cardiomyo...
ETVs dictate hPSC differentiation by tuning biophysical properties Stem cell interactions involve biochemical and biophysical cues, but the transcriptional control of biophysical traits is unclear. This study identifies ETVs as regulators of adhesion in hPSCs and pancreatic progenitors, shaping lineage deci...
Human pluripotent stem-cell-derived islets (hPSC-islets) are a promising cell resource for diabetes treatment1,2. However, this therapeutic strategy has not been systematically assessed in large animal models physiologically similar to humans, such as non-human primates3. In this study, we generated...
Erratum: Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells (Stem Cell Reports (2014) 2 (838-852)) R Forster,K Chiba,L Schaeffer,... - 《Stem Cell Reports》 被引量: 0发表: 2014年 Generating human intestinal tissues from pluripotent stem cells to ...
Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis Aside from the well-established self-renewal and multipotent differentiation properties, mesenchymal stem cells exhibit both immunomodulatory and...
Sources of pluripotent stem cells PSCs are characterized by the properties of self-renewal and potency, wherein the former refers to the cell’s ability to proliferate and the latter refers to the cell’s ability to differentiate into specialized cell types derived from one of three primary germ...
Pluripotent stem cells (PSCs) hold great potential for novel therapeutic approaches to regenerate or replace functionally impaired tissues. Since the introduction of the induced pluripotent stem cell technology in 2006, the number of scientific publications on this topic has constantly been increasing. ...
Induced pluripotent stem cells are different from embryonic stem cells as shown by epigenetic and genomics analyses. Depending on cell types and culture conditions, such genetic alterations can lead to different metabolic phenotypes which may impact replication rates, membrane properties and cell differenti...
Mesenchymal stem cells (MSCs). A type of multipotent adult stem cell found in the stroma, or connective tissue, of a variety of different organs. In addition to multipotent differentiation capabilities, they have immunomodulatory properties that may be beneficial in treating autoimmune, degenerative an...