Covas Dimas T.de Castro Fabiola A.Journal of Cell ScienceAline F, Ferreira,George A,etc.Hematopoietic stem cells from induced pluripotent stem cells - considering the role of microRNA as a cell differentiation regulator.[J].2018,131(4)....
role in platelet production, but is not essential for this. CFU-Mast differentiates as mast cells after cell activation in response to SCF and IL-3, also to IL-4 (interleukin-4), IL-5, and IL-9 (interleukin-9). IL-4 enhances ...
Defined culture conditions robustly maintain human stem cell pluripotency, highlighting a role for Ca2+ signaling Comparative analysis of 100+ PSC lines highlights biological differences between defined and undefined culture conditions. Standardization reduces PSC variability, maintains self-renewal, and en...
Thus, it is not surprising that expression of CD4 on pluripotent stem cells has been missed previously. Taken together, our data suggest that the CD4 molecule may play an important role in lineage definition in early hematopoietic differentiation.© 1992 by The American Society of Hematology....
The role of c-kit in the maintenance and survival of hematopoietic stem cells and of mast cells is well recognized. c-kit also plays an important ... P Ray,N Krishnamoorthy,A Ray - 《Cell Cycle》 被引量: 106发表: 2008年 c-Myc is essential for hematopoietic stem cell differentiation and...
The hematopoietic system is maintained by a rare population of hematopoietic stem cells (HSC) that are thought to undergo self-renewal as well as continuou... K Ohishi,B Varnum-Finney,ID Bernstein - 《International Journal of Hematology》 被引量: 124发表: 2002年 Role of voltage-gated potassium...
The urge to have one’s own biological child supersedes any desire in life. Several options have been used to obtain gametes including pluripotent stem cells (embryonic ES and induced pluripotent iPS stem cells); gonadal stem cells (spermatogonial SSCs,
In this study, we generated alveolar organoids (AOs) derived from human pluripotent stem cells (hPSCs) for use as an PF model and for drug efficacy evaluation. Stepwise direct differentiation of hPSCs into alveolar epithelial cells by mimicking developmental cues in a temporally controlled manner ...
Human pluripotent stems cells provide an ideal source for the study of hematopoietic differentiation. Natural killer (NK) cells are lymphocytes that play a key role in innate immunity against viral infections as well as malignancies. The development and differentiation of NK cells have been an area...
In particular, we focus on the role of RUNX1 in hematopoietic stem cells (HSCs) and hair follicle stem cells (HFSCs) and the importance of the solo... PJ Appleford,A Woollard - 《Journal of Cellular Biochemistry》 被引量: 45发表: 2010年 Expression of the runt homology domain of RUNX1...