plasma cellssmolderingWaldenström macroglobulinemiaPlasma cell disorders encompass a number of diagnostic entities, with the most common being multiple myeloma. These disorders typically affect multiple organ systems, and patients can present with a spectrum of symptoms. Evaluation of these disorders ...
Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, ... Multiple myeloma (MM) cells inhibit certain T-cell functions. We examined the expression of B7-H1 (PD-L1), a B7-related ...
Burkitt's type translocation in multiple myeloma karyotypeplasmacellsT(822)We report a case of multiple myeloma with a t(8;22)(q24;q11) found during the progression of the disease. The relation ... F.,Solé,and,... - 《Leukemia Research》 被引量: 11发表: 1994年 Prevalence of p16 Met...
Microarray analyses and gene targeting have recently enhanced the understanding of factors involved in normal plasma cells and multiple myeloma. Plasma cells develop from marginal zone or germinal center B cells following stimulation by antigen, microbial products, TNF family signals and cytokines. Transcr...
plasma cellsmultiple myelomaplasma cell leukemiaThe aim of this prospective, long-term study was to define the flow cytometric characteristics of plasma cell CD56 expression as well as determine the clinical characteristics of 204 multiple myeloma (MM) patients and 26 plasma cell leukemia (PCL) ...
Multiple myeloma (MM) is a cancer caused by proliferation of a clonal population of plasma (antibody-producing) cells in the bone marrow, which results in excess monoclonal immunoglobulin in the serum, anaemia, hypocalcemia, renal insufficiency and/or bone lesions in addition to recurrent infections...
Plasma cells use P2RX4 to sense the regulated release of ATP from osteoblasts and this protects against ER stress-driven apoptosis. Yvonne Bordon Research Highlights29 Feb 2024 Nature Reviews Immunology Volume: 24, P: 231 Tissues of origin matter to plasma cell longevity Anatomical separation ...
Burkitt's type translocation in multiple myeloma karyotypeplasmacellsT(822)We report a case of multiple myeloma with a t(8;22)(q24;q11) found during the progression of the disease. The relation ... F.,Solé,and,... - 《Leukemia Research》 被引量: 11发表: 1994年 Plasma cell myeloma ...
Monoclonal plasma cells in the blood stem cell harvest from patients with multiple myeloma are associated with shortened relapse-free survival after transp... We sought to determine whether circulating tumor cells in the blood stem cell harvest from patients with multiple myeloma are associated with ...
Plasma cells, including a long-lived subset, reside in the bone marrow where they depend on poorly defined microenvironment-linked survival signals1. We show that bone marrow plasma cells use the ligand-gated purinergic ion channel P2RX4 to sense extracellular ATP released by bone marrow ...