651. Multiple Myeloma and Plasma Cell Dyscrasias- Basic and Translational- Micro002024-12-17 21:05:37您当前的浏览器不支持 HTML5 播放器 请更换浏览器再试试哦~点赞 投币 收藏 分享 ASH 知识 科学科普 课程 英语 科学 Domi呀 发消息 信息搬运站-Domi 接下来播放 自动连播 301. Platelets and Megakary...
F. Differences in genetic changes between multiple myeloma and plasma cell leukemia demonstrated by comparative genomic hybridization. Leukemia (Baltimore), 15: 840 - 845, 2001.Gutierrez NC, Hernandez JM, Garcia JL, Canizo MC, Gonzalez M, Hernandez J, et al. Differences in genetic changes ...
Plasma cells in Multiple Myeloma express a natural killer cell-associated antigen:CD56 (NKH-1; Leu19) Bone marrow samples from 55 patients with multiple myeloma (MM) and 23 patients with monoclonal gammopathy of undertermined significance (MGUS) were evaluated with a broad panel of monoclonal ...
Multiple myeloma and plasma cell disroders audit on behalf of the West Midlands Regional Audit GroupRankin, NBignell, M
In a patient with threefold malignancy, chronologically hypernephroma, carcinoma of the colon and plasma cell myeloma, the latter was associated with an unusual M protein of Gm4 type, antigenically deficient when compared to reference proteins of the γG1 heavy chain subclass. The patient suffered...
Transcription factors, B-lymphocyte-induced maturation protein 1 (Blimp-1) and X-box binding protein 1 (XBP-1) are required for plasma cell development. They regulate sets of genes that induce immunoglobulin secretion, halt proliferation and block alternative B-cell fates. In multiple myeloma, ...
The current definition of plasma cell leukemia (PCL)— ≥ 20% circulating plasma cells (CPCs) on peripheral smear and plasma cell count ≥ 2 × 109/L—may be too stringent. We reviewed outcomes of 176 multiple myeloma (MM) patients diag
Multiple myeloma (MM) is a plasma cell disorder arising from bone marrow, and the lipid status of MM cells has not been reported yet. In this study, we analyzed flow cytometry-sorted single MM cells and normal plasma cells (NPCs) using matrix-assisted laser desorption/ionization–imaging mass...
In multiple myeloma and related plasma cell dyscrasias, either FDG PET or PET-CT imaging is useful and reliable technique for diagnosis by identifying optimal sites for biopsy, for staging and restaging the tumor, for detecting extramedullary disease and monitoring response to treatment, though PET-...
Plasma cell differentiation is regulated by the expression of histone variant H3.3 During plasma cell differentiation, H3.3 histone variant is downregulated, and the H3.3 deposition and chromatin accessibility are dynamically changed. Blockade of H3.3 downregulation by enforced H3.3 expression impairs pl...