leukemiaPlasma cell leukemia (PCL) can be considered the leukemic variant of multiple myeloma. The diagnosis is based on hematological features, including a plasmacytosis exceeding 2 脳 109/l and any evidence of a clonal plasma cell proliferation. There are two forms of PCL: the primary form ...
Condition:Plasma Cell Leukemia Plasma cell leukemia (PCL) is an aggressive form of multiple myeloma characterized by high levels of abnormal plasma cells circulating in the peripheral (circulating) blood. Normal plasma cells in the bone marrow produce antibodies that fight infection. ...
Plasma cell leukemia is an unusual manifestation of multiple myeloma, reported to occur in 2% of newly diagnosed patients. It may either present at the time of diagnosis (primary) or evolve as a late feature in the course of multiple myeloma (secondary). Most clinical signs of myeloma are ob...
摘要: Plasma cell leukemia (PCL) is a rare and aggressive form of multiple myeloma (MM). It is characterized by the presence of a large number of circulating clonal plasma cells. It is comprised of two form关键词: Plasma cell leukemia Circulating plasma cells Extramedullary myeloma ...
Related to plasma cell leukemia:plasma cell myeloma leu·ke·mi·a (lo͞o-kē′mē-ə) n. Any of various acute or chronic neoplastic diseases of the bone marrow in which unrestrained proliferation of white blood cells occurs, usually accompanied by anemia, impaired blood clotting, and enlar...
The current definition of plasma cell leukemia (PCL)— ≥ 20% circulating plasma cells (CPCs) on peripheral smear and plasma cell count ≥ 2 × 109/L—may be too stringent. We reviewed outcomes of 176 multiple myeloma (MM) patients diagnosed between 1971 and 2016, and who ha...
Plasma cell leukemia (PCL) is an aggressive variant of multiple myeloma and is characterized by the presence of >20% and/or an absolute number of greater 2×10(9)/L plasma cells circulating in the peripheral blood. PCL represents approximately 2–4% of all MM diagnosis and exists in two ...
plasma cell (redirected fromPlasma cells) Thesaurus Medical Encyclopedia Related to Plasma cells:Macrophages,Histiocytes,Memory cells n. Any of various short-lived cells that develop from activated B cells and secrete large numbers of antibodies. They are found chiefly in the bone marrow, spleen, ...
Purpose: Plasma cell leukemia (PCL) is a rare form of plasma cell dyscrasia that presents either as a progression of previously diagnosed multiple myeloma,... K Todoerti,L Agnelli,S Fabris,... - 《Clinical Cancer Research An Official Journal of the American Association for Cancer Research》...
plasma cell- a cell that develops from a B lymphocyte in reaction to a specific antigen; found in bone marrow and sometimes in the blood plasmacyte lymph cell,lymphocyte- an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence ...