Plasma cell dyscrasias particularly comprise multiple myeloma, Waldenstrom's macroglobulinemia, monoclonal gammopathy of undetermined significance (also called benign monoclonal gammopathy), and (rarely) lymphoma or lymphocytic leukemia. Multiple myeloma (MM) is a B-cell cancer characterized by proliferation ...
CHICAGO, June 5 (Xinhua) -- Chinese scientists presented a possible cell therapy for multiple myeloma at the 2017 annual meeting of the American Society of Clinical Oncology (ASCO) held here in Chicago on Monday. Data collected by Chinese scientists in an early clinical trial show that the the...
This is the general mechanism how genetic transformation of plasma cells leads to development of multiple myeloma in mostly elderly individuals. The abnormal plasma cells overflow from the bone marrow of origin and via blood are transported to bone marrow in other parts of the body. Thus, bone m...
Discover cutting-edge multiple myeloma cancer treatment options at Berenson Cancer Center. Led by Dr. James Berenson, we specialize in personalized care and advanced research.
Multiple Myeloma Multiple myeloma, also known as Kahler's disease, is a type ofblood cancer. There's no cure, but treatments can slow its spread and sometimes make symptoms go away. A type of white blood cell called a plasma cell makes antibodies that fight infections in your body. When ...
浆细胞病(Plasma cell dyscrasias) 多发性骨髓瘤(Multiple Myeloma)定义和特性;What Is Multiple Myeloma?;浆细胞病(Plasma cell dyscrasias);隐性浆细胞病良性单克隆免疫球蛋白血症;继发性单克隆免疫球蛋白血症。病因:尚未完全明了可能与遗传有关,有染色体异常病毒感染继发于其他疾病(慢性骨髓炎、结核、慢性肝炎);M...
Multiple myeloma is a plasma cell blood cancer with frequent chromosomal translocations leading to gene fusions. To determine the clinical relevance of fusion events, we detect gene fusions from a cohort of 742 patients from the Multiple Myeloma Research Foundation CoMMpass Study. Patients with multip...
differentiatemultiple myelomafrom other plasma cell dyscrasias; however, several factors may suggest this diagnosis. SerumM proteingreater than 3 g/dL,Bence Jonesproteinuria, presence of more than 10% plasma cells in the bone marrow, osteolyic lesions, increased plasma cell labeling index, anemia,...
Multiple myeloma is an incurable plasma cell malignancy that is mostly restricted to the bone marrow. Cancer-induced dysfunction of cytotoxic T cells at the tumor site may be responsible for immune evasion and therapeutical failure of immunotherapies. Therefore, enhanced knowledge about the actual stat...
Whitehouse on the project, said: "We will insert a genetically-engineered adenovirus of the type previously used in clinical studies into the Multiple Myeloma cell culture in our lab to deliver molecules that will specifically trigger a reduction in the IRF4 protein levels within the cancer cells...