NAcHis-TPGS)修饰到聚乙丙交酯[poly(lactic-co-glycolic acid), PLGA]纳米粒表面,并包载多柔比星(doxorubicin, DOX)及光敏剂吲哚菁绿(indocyanine green, ICG),在血液循环中该纳米粒呈负电特性,到达肿瘤细胞外,组氨酸发生质子化呈正电性,迅速被肿瘤细胞摄取(图3)。
AcidDissociationConstants Ionicstrength(,)(0),0.1M§ NameStructure*pKa†Ka‡pKa† AceticacidCH3CO2H4756175(10)5456(ethanoicacid) NH3, 2337153(10)336(10)10344(CO2H)868(NH3)HCH3O2Hlanine 46451(10)5601H3,minobenzeneaniline) 30186(10)4232O3SNH3,-Aminobenzenesulfonicacidsulfanilicacid) ...
Moreover, Indications For Glycolic Acid Peels Tend To Be Restricted To The Treatment Of Sun-Damaged Or Acneic Skin, Especially In Patients Who Cannot Or Do Not Want Their Skin To Flake, Often Because Of Their Professional Activities, Which Are Incompatible With Visible Peeling....
In the present study, L-dopa and benserazide were loaded by poly (lactic-co-glycolic acid) microspheres (LBM), which can release levodopa and benserazide in a sustained manner in order to continuous stimulate dopaminergic receptors. We investigated the role of striatal DR1/PKA/P-tau signal ...
Hung 等[8]将N-乙酰组氨酸偶联维生素E 聚乙二醇琥珀酸酯(N-acetyl histidine-D-αtocopheryl polyethylene glycol succinate, NAcHis-TPGS)修饰到聚乙丙交酯[poly(lactic-co-glycolic acid), PLGA]纳米粒表面,并包载多柔比星(doxorubicin, DOX)及光敏剂吲哚菁绿(indocyanine green, ICG),在血液循环中该纳米粒呈...
Baseline separation of 6 inorganic (e.g., nitrite, nitrate and sulfate) and 5 organic anions (e.g., acetic and glycolic acid) was achieved. Quantification of 8 out of 11 specified anions was possible in stressed engine coolant samples after simple aqueous dilution. LODs between 0.8 and 15.1...
In this paper, four different organic acids, including formic acid, glycolic acid, lactic acid, and acetic acid were selected to compare their hydrolytic effects. Results Using pKa values as the benchmark, the yield of xylo-oligosaccharide (XOS) increased with the increasing value of pKa. The ...
Hung 等[8]将N-乙酰组氨酸偶联维生素E 聚乙二醇琥珀酸酯(N-acetyl histidine-D-αtocopheryl polyethylene glycol succinate, NAcHis-TPGS)修饰到聚乙丙交酯[poly(lactic-co-glycolic acid), PLGA]纳米粒表面,并包载多柔比星(doxorubicin, DOX)及光敏剂吲哚菁绿(indocyanine green, ICG),在血液循环中该纳米粒呈...