Section 11:Chemotherapy Section 12:General Features: Drug Toxicity and Prescribing Select Index Book chapterFull text access Index Pages 707-729 View PDF View chapter About the book Description Medical Pharmacology & Therapeutics, now in its fifth edition, offers medical students all they need to kno...
It focuses on understanding the actions and metabolism of drugs and toxic substances, as well as defining mechanisms of action in various areas such as cancer chemotherapy, neuropharmacology, and cardiovascular pharmacology. AI generated definition based on: Information Resources in Toxicology (Fourth ...
Despite the therapeutic benefit, these antibodies either do not have the desired clinical efficacy or have to be co-administered with traditional chemotherapy. These shortcomings of mAbs led to efforts to enhance the therapeutic benefit of mAbs by modifications, mainly by forming a conjugate [1]. ...
but much less is known of their pharmacodynamics, that is of the relationship between therapeutic or toxic response and drug concentration. Drug dosage regimens which are to achieve defined therapeutic objectives can only be designed when both the pharmacokinetic and the pharmacodynamic characteristics...
Kaufmann, S.H.E. Paul Ehrlich: founder of chemotherapy.Nat. Rev. Drug Discov.7, 373 (2008). CASPubMedGoogle Scholar Zambrowicz, B.P. & Sands, A.T. Modeling drug action in the mouse with knockouts and RNA interference.Drug Discov. Today Targets3, 198–207 (2004). ...
Lecture notes: introduction to ocular pharmacology, ocular route of drug administration, chemotherapy, antibiotics, antiviral and antifungal drugsdoi:10.13140/RG.2.2.30686.25925Nizar Jassem
Exam 2 Classes & Drug Names 23個詞語 本學習集中的詞語(102) · Individual Variation in Drug Responses o Due to numerous major factors, responses to medications will be varied amongst all patients. Drug therapy will be tailored to maximize treatments and minimize potential for harm. ...
The availability of systematic drug response registries for hundreds cell lines, coupled with the comprehensive profiling of their genomes/transcriptomes enabled the development of computational methods that investigate the molecular basis of drug responsiveness. Herein, we propose an automated, multi-omics ...
there are a number of drugs that do not fall within those classes but that demonstrate anticancer activity and thus are used in the treatment of malignant disease. The termchemotherapyfrequently is equated with the use of anticancer drugs, although it more accurately refers to the use of chemical...
et al. The use of four-drug combination chemotherapy (D.A.V.E.) in the treatment of advanced Wilms' tumour. Cancer Chemother. Pharmacol. 5, 211–215 (1981). https://doi.org/10.1007/BF00434386 Download citation Received03 November 1980 Accepted13 January 1981 Issue DateJune 1981 DOIhttps:...