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tubulin-binding drugstopoisomerase inhibitorsmiscellaneous agentsSummary This chapter contains sections titled: Classification of drugs ReferencesLouise Soanes RSCN RGN MSc BSc (Hons) Senior SisterPaediatric Oncology Unit, John Radcliffe Hospital, Headington, Oxford, UK...
Pancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers in part because it is insensitive to many chemotherapeutic drugs. Studying a ... KP Olive,MA Jacobetz,CJ Davidson,... - 《Science》 被引量: 4421发表: 2009年 Efficacy of adjuvant chemotherapy after curative resection...
Some chemotherapy drugs can affect cells only in specific phases of the cell cycle (phase specific), whereas other drugs act during any phase of the cell cycle (phase nonspecific). A general biochemical classification of chemotherapy agents includes alkylating agents, plant alkaloids, antimetabolites,...
Gastric cancer exhibits varied sensitivity to chemotherapy drugs and significant heterogeneity; therefore, the disease may be a target for individualized therapy. The Lauren classification may provide the basis for individualized treatment for advanced gastric cancer, which is increasingly gaining attention ...
Classification of antiemetics See Table 17.7. Table 17.7. Summarizing different classes of antiemetic drugs and their special uses. S. no.Class of drugsDrugsUses 1 5-HT3 antagonist Ondansetron Palonosetron Chemotherapy-induced nausea, vomiting Postoperative nausea vomiting 2 D2 antagonist Phenot...
Despite wider application of sophisticated immunological and genetic studies both at diagnosis or later, recognising poor-prognosis children prospectively is hampered by the lack of a biological classification system that is sufficiently sensitive and specific to categorise all patients reliably. In those ...
associated with the plasma membrane). Moreover, the apoptotic execution phase can involve a variable degree of caspase-dependent and caspase-independent catabolic reactions, meaning that similar morphologies may have been acquired through distinct biochemical routes. As a result, the classification of ...
Depending on the disease stage and subtype classification, breast cancer treatment typically employs a multi-modal treatment approach using combinations of surgery, chemotherapy, endocrine therapy, and radiotherapy. The mainstay of therapy is, however, chemotherapy combined with surgery, particularly in ...
Over the last two decades, new chemotherapeutic agents have been used for the treatment of cancer with remarkable efficacy. Despite these positive effects, several dermatologic adverse events have emerged such as xerosis, alopecia, papulo-pustular rash, nail damage, trichomegaly, hand–foot syndrome...