In this review, we discuss recent advances in the development of pH-sensitive nanocarriers for tumour-targeted drug delivery. The review focuses on the chemical design of pH-sensitive biomaterials, which are used to fabricate nanocarriers for extracellular and/or intracellular tumour site-spec...
Thein vitrocytotoxicity of the drug-loaded micelles towards MCF-7/ADR cells was evaluated using the MTT method43. The cells were seeded in 96-well plates at a density of 5 × 103cells per well and incubated for 24 h. Then, the growth medium was replaced with fresh medium containing...
Preparation of Magnetic pH-Sensitive Film With Alginate Base for Colon Specific Drug Delivery[J] . Abdolrahim Abbaszad Rafi,Mehrdad Mahkam.International Journal of Polymeric Materials and Polymeric Biomaterials . 2015 (4)Abbaszad Rafi, A., Mahkam, M., 2015a. Preparation of magnetic pH-sensitive...
Biomaterials 23 (2002) 343–347 Preparation of oxidized glucose-crosslinked N-alkylated chitosan membrane and in vitro studies of pH-sensitive drug delivery behaviour Fang Li, Wen Guang Liu, Kang De Yao* Research Institute of Polymeric Materials, Tianjin University, Tianjin 300072, People’s ...
Novel pH- sensitive carriers containing naproxen pendant groups for colon-specific drug delivery. Int J Polym Mater. 2011;60:1- 10.Mahkam, M. and Poorgholy, N. Novel pH-sensitive carriers containing naproxen pendant groups for colon-specific drug delivery. Int. J. Polym. Mater. 2010, 60,...
The development of immunoliposomes for systemic siRNA (small interfering RNA) delivery is highly desired. We reported previously the development of targete... J Gao,Y Yu,Y Zhang,... - 《Biomaterials》 被引量: 137发表: 2012年 Enhanced Growth Inhibition of Hepatic Multicellular Tumor Spheroids by...
Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery Biomaterials, 34 (2013), pp. 3647-3657 View PDFView articleView in ScopusGoogle Scholar [17] L. Zhang, Y. Qin, Z. Zhang, F. Fan, C. Huang, L. Lu, H. Wang, X. Jin, H. Zhao, D. ...
Nanotechnology-based drug delivery systems have been intensively investigated, while only a few of them can be used for clinic application. Hematoporphyrin... Yu,Ren,Ruirui,... - 《Biomaterials》 被引量: 24发表: 2014年 Targeted and regional cellular ablation in zebrafish A system including: (i...
Gelatin-Encapsulated Magnetic Nanoparticles for pH, Redox, and Enzyme Multiple Stimuli-Responsive Drug Delivery and Magnetic Resonance Imaging Lu, "Multifunc- tional envelope-type mesoporous silica nanoparticles for pH- responsive drug delivery and magnetic resonance imaging," Biomaterials, vol. 60,... ...
The title drug delivery system comprises neg. charged drug prepn., and injectable and biodegradable temp.- and pH-sensitive (hydrophilic and hydrophobic) block copolymer hydrogel. The neg. charged drug prepn. is packaged in the injectable biodegradable temp.- and pH-sensitive blo...