This chapter explicitly provides a comprehensive account of the importance of pH at the organ, tissue, and cellular level for drug delivery, the type of biomaterials along with the chemical modifications needed to achieve the pH-dependent drug release, the mechanism of drug release, and their ...
62. Prabaharan M, Grailer JJ, Pilla S, Steeber DA, Gong S (2009) Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery. Biomaterials 30:5757–5766. https://doi.org/10.1016/j.biomaterials.2009.07.020 63. Ma YK, Fan...
[13] Drummond D C, Zignani M, Leroux J C. Current Status of pH-Sensitive Liposomes in Drug Delivery[J]. Progress in Lipid Research, 2000, 39(5): 409-460. [14] Venugopalan P, Jain S, Sankar S, et al. pH-Sensitive Liposomes:Mechanism of Triggered Release to Drug and Gene Delivery...
In the present study, an endosomal, pH-sensitive, mixed micellar delivery system with a folate targeting ligand based on the pH-sensitive copolymer PHis-PLA-PEG-PLA-PHis and Pluronic F127 (F-pHSM-L61/CUR/DOX) was constructed for the intracellular co-delivery of the small modulating molecule...
2023, Biomaterials Advances Show abstract Rapid-dissolving electrospun nanofibers for intra-vaginal antibiotic or probiotic delivery 2023, European Journal of Pharmaceutics and Biopharmaceutics Show abstract pH and its applications in targeted drug delivery 2023, Drug Discovery Today Citation Excerpt : It off...
Preparation of Magnetic pH-Sensitive Film With Alginate Base for Colon Specific Drug Delivery[J] . Abdolrahim Abbaszad Rafi,Mehrdad Mahkam.International Journal of Polymeric Materials and Polymeric Biomaterials . 2015 (4)Abbaszad Rafi, A., Mahkam, M., 2015a. Preparation of magnetic pH-sensitive...
pH-Sensitive biodegradable polymethacrylic acid-block-polylactic acid-block-polymethacrylic acid (PMAA2-b-PLA-b-PMAA2) H-type multiblock copolymers were synthesized by atom transfer radical polymerization. The copolymer structure and molecular weight were characterized by FT-IR, 1H NMR, and gel perme...
A peptide-based pH-sensitive drug delivery system for targeted ablation of cancer cells 来自 掌桥科研 喜欢 0 阅读量: 83 摘要: A peptide-guided prodrug incorporating a tumor-specific peptide, doxorubicin, and a pH-sensitive hydrazone bridge was developed for targeted ablation of cancer cells with...
Biodestruction of doxorubicin and nanostructured ferrocarbon carrier particles in organism during magnetically controlled drug delivery Z Gao,C You,H Wu,... - 《Journal of Biomaterials Science Polymer Edition》 被引量: 3发表: 2017年 Targeted delivery to human diseases and disorders The present invent...
siRNA Delivery by Stimuli-Sensitive Nanocarriers Since its discovery in the late 1990, small interfering RNA (siRNA) have quickly crept into the biopharmaceutical research as a new and powerful tool for t... G Salzano,DF Costa,VP Torchilin - 《Current Pharmaceutical Design》 被引量: 10发表: ...