The eye has a specific environment for pharmacokinetics. Topically administered drugs with eye drops cannot easily reach the posterior segments of the eye. Also systemic administration cannot easily exhibit drug efficacy on vitreoretinal diseases. On the basis of this difficulty in drug delivery into ...
相关论文以题为Mechanically Matching the Rheological Properties of Brain Tissue for Drug-Delivery in Human Glioblastoma Models发表在《Biomaterials》上。通讯作者为剑桥大学的Oren A.Scherman教授。 主图 图1. HACF(x) 是通过简单易行的化学方法产生的。CB[8] 表现出对 HACF(10) 苯丙氨酸基团的客体选择性...
Nanoengineered Biomaterials for Advanced Drug Deliveryexplores the latest advances in the applications of nanoengineered biomaterials in drug delivery systems. The book covers a wide range of biomaterials and nanotechnology techniques that have been used for the delivery of different biological molecules and...
Langer was honored with MRS's highest award for his "pioneering accomplishments in the science and application of biomaterials in drug delivery and tissue engineering, particularly in inventing the use of materials for protein and DNA delivery, and for his achievements in interdisciplinary research ...
Here, strategies for the design and implementation of biomaterials for drug delivery are reviewed. A brief history of the biomaterials field is first established, and then commentary on RNA delivery, responsive materials development, and immunomodulation are provided. Current challenges associated with ...
the delivery of different biological molecules and drugs in the human body. It is an important resource for biomaterials scientists and engineers working in biomedicine and those wanting to learn more on how nanoengineered biomaterials are being used to enhance drug delivery for a variety of ...
The use of nanotechnology as sustained drug delivery platforms in medicine has been an active research field over the past decade. Nano-formulations are also currently being explored for macromolecule drug delivery to the posterior segment of the eye. There are many various nano-formulations such as...
A second area, tissue engineering, is also discussed. New polymer systems for creating cartilage, blood vessels, nerves, and other tissues are examined. 展开 关键词: Animals Humans Biocompatible Materials Drug Delivery Systems Biosensing Techniques Biomedical Engineering Artificial Organs ...
Cross-linked hyaluronic acid hydrogel films: new biomaterials for drug delivery A new hyaluronic acid (HA)-based hydrogel film was prepared and evaluated for use in drug delivery. This biocompatible material crosslinks and gels in minu... L Yi,KR Kirker,GD Prestwich - 《Journal of Controlled ...
Gelatin/chondroitin 6-sulfate microspheres for the delivery of therapeutic proteins to the joint Objective To develop a biodegradable, inflammation-responsive microsphere system for the intraarticular delivery of therapeutic proteins. Methods Microspheres were synthesized by complex coacervation. Radiolabeled prot...