pH-responsive polymerspolyelectrolytessmart nanocarrierssmart polymerstargeted drug deliveryPolymer science has applications in biomedical engineering, prosthetics, surgical implants, and prospective pharmaceutical excipients for drug delivery. "Intelligent or Smart Polymers" are created for drug targeting either by...
pH-Responsive Polymer Nanoparticles for Drug Delivery Nayeleh Deirram, Changhe Zhang, Sarah S. Kermaniyan, Angus P. R. Johnston, Georgina K. Such School of Chemistry, The University of Melbourne, Parkville, Victoria, 3010 Australia Macromolecular Rapid Communications, Volume40, Issue10 Special ...
(2013) Ultrasound and pH dually responsive polymer vesicles for anticancer drug delivery. Sci. Rep. 3, 2162Chen, W. Q. & Du, J. Z. Ultrasound and pH dually responsive polymer vesicles for anticancer drug delivery. Sci. Rep. 3, 2162 (2013)....
For example, there are no temperature or electrical field responsive polymer vesicles used for the drug delivery in clinic due to the lack of appropriate polymers; UV-responsive polymers are not ideal for the biomedical applica- tions due to the risk of UV light to the skin. Compared to the...
Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications, Vol. 2: Advanced Nanocarriers for Therapeutics, A.S. Hamdy Makhlouf and N. Y. Abu-Thabit (Editors): "Recent Trends in Designing Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications", ... ASH Makhlouf,NY...
纳米聚合物胶束通过EPR效应将抗肿瘤药物传递和积累到肿瘤组织,实现有效的靶向给药系统(transdermal drug delivery systems,TDDS)[39]。然而,聚合物药物在到达肿瘤部位前释放过快会引起毒副作用,降低靶区药物浓度;而释放过慢会降低靶区药物疗效,增加肿瘤细胞的耐药性。为了克服这些障碍,研究设计对环境敏感的聚合物,可以...
SS West - 《Advanced Drug Delivery Reviews》 被引量: 343发表: 2002年 Magnetothermally-responsive Nanomaterials: Combining Magnetic Nanostructures and Thermally-Sensitive Polymers for Triggered Drug Release This paper reviews the design and development of magnetothermally-triggered drug delivery systems, wher...
carriers have been used in targeted antitumor drug delivery;it can reduce side effects of anticancer drugs and improve chemotherapeutic index.In this paper we reviewed the main synthetic strategies of polymeric micelles with pH-responsive structure and its applications as delivery system for anticancer ...
15), which is consistent with the previously reported lack of toxicity of the ATRAM peptide at either physiological or acidic pH55. Taken together, the cell viability results suggest that the designed ATRAM-BSA-PLGA NPs are nontoxic and compatible for use as a pH-responsive drug delivery ...
Taken together, the cell viability results suggest that the designed ATRAM-BSA-PLGA NPs are nontoxic and compatible for use as a pH-responsive drug delivery system. Fig. 6: Mechanism of pH-dependent cytotoxicity of Dox-TPP loaded ATRAM-BSA-PLGA NPs. a Cell viability of MCF-7 cells treated...