Mesenchymal stem cell-con- ditioned media ameliorate diabetic endothelial dysfunc- tion by improving mitochondrial bioenergetics via the Sirt1/AMPK/PGC-1alpha pathway[J]. Clin Sci(Lond), 2016,130(23):2181-2198. [12] 袁勇,邢建国,王立萍,等.香青兰总黄酮在大鼠体内的药 代动力学研究[J].石河子...
Physiology Evaluating the PGC-1 alpha pathway and a new preclinical model to advance treatment options for dystrophinopathies IOWA STATE UNIVERSITY Joshua T. Selsby HollingerKatrinDuchenne muscular dystrophy (DMD) is caused by a mutation in the dystrophin gene leading to the production of a non...
PPAR gamma/PGC-1 alpha Pathway in E-Cadherin Expression and Motility of HepG2 Cells (vol 29, pg 5057, 2009)Thymosin beta4 (Tbeta4), the actin-... HJ Lee,CW Chi - 《Anticancer Research》 被引量: 1发表: 2010年 Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-...
PGC-1alpha induces apoptosis in human epithelial ovarian cancer cells through a PPARgamma-dependent pathway[J]. Cell Res, 2007, 17(4): 363. [2] 贾敏茹,李星炜. 中国民族志要[M]. 北京:中国医学科技出版社,2005. [3] 马宗超,唐智宏,张海. 谈附子的药理及临床应用[J].时珍国医国药, 2004, ...
虽然 【8】“nJ,WuH,Ta盯Pt drivesthef溉tionofslow—t而tch AMPK也可能调节NRFl/2和mfrFA的表达,但多数研究认为1alpha mu∞lem嘲叨.Na— P(七一la为AMPK调节线粒体生物合成最主要的下游靶。 t山弓2002,418:797—801. 虽然陆续发现了N0、MEF2及P38MAPK等AMPK作用 RC.Mi眦hon“alDNA 【9】HuoL,Scar...
关键词:利格列汀;糖尿病肾脏疾病;线粒体生物合成;AMPK/PGC-1α/TFAM 信号通路 Linagliptin improves diabetic kidney disease in rats by promoting mitochondrial biogenesis through the AMPK/PGC-1α/TFAM pathway WAN Lu1, QIAN Yuchi1, 3, NI Wenjing1, 2, LU Yuxin1, LI Wei1, PAN Yan1, CHEN Wei...
7A novel polymorphism in protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2) is associated with type 2 diabetes in the Han Chinese population期刊论文Shen,Jizhong|Ge,Weihong|Fang,Yun|Liu,Hang| 南京大学---近十年中标数量情况分析 南京...
Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype.Cell Metab. 2008; 8: 249-256Abstract Full Text Full Text PDF PubMed Scopus (264) Google Scholar), were stable in gastrocnemius of control mice between 14 and 30 ...
除UCP1外,氧化物酶体增殖物激活受体γ辅激活因子1α(Peroxisome Proliferator-Activated Receptor gamma Coactivator 1-alpha,PGC-1α),纤维连结蛋白III型域包含蛋白5(Fibronectin Type III Domain-Containing protein 5,FNDC5)和Irisin也是白色脂肪棕色化中的重要信号分子。PGC-1α是一种辅助转录因子,能够通过调节线粒...
Effect of nicotinamide regulating glycolysis metabolism on leukemic cell HL-60 through SIRT1/PGC-1 alpha/HIF2 alpha pathway Objective: To investigate the effect of nicotinamide regulating the glycolysis metabolism on leukemia cell line HL-60, and explore the role of SIRT1/PGC-1... M Liu,P Zho...