CONCLUSION: PPARgamma/PGC-1alpha pathway plays a crucial role in modulating E-cadherin expression and motility of HepG2 cells and may be a potential target for the prevention of HCC metastasis. 展开 关键词: siRNA migration metastasis hepatocellular carcinoma peroxisome proliferator-activated receptor...
PGC-1alpha induces apoptosis in human epithelial ovarian cancer cells through a PPAR- gamma-dependent pathway. Cell Res 2007;17:363-73.Zhang Y, Ba Y, Liu C, Sun G, Ding L, Gao S et al. (2007). PGC- 1alpha induces apoptosis in human epithelial ovarian cancer cells through a PPAR...
Baicalin increases VEGF expression and angiogenesis by activating the ERRα/PGC-1α pathway. Aims Baicalin is the major component found in Scutellaria baicalensis root, a widely used herb in traditional Chinese medicine. Although it has been used f... Zhang,Keqiang,Lu,... - 《Cardiovascular Rese...
ERR (oestrogen-related receptor)-alpha modulates the oestrogen signalling pathway and regulates genes participating in the physiological energy balance programme. Oestrogen and PGC-1alpha (peroxisome proliferator-activated receptor-gamma coactivator-1alpha), the master regulator of the energy homoeostasis pro...
A very tangible consequence of this relationship emerges from our examination of this pathway during exercise under physiological and disease conditions. Physical exercise requires energy sources in the form of ATP mostly derived from mitochondria. Physical exercise is an established inducer of PGC-1α ...
油酸对小鼠hepa1-6细胞PGC-1α的影响及其信号通路The effect of oleic acid on PGC-1 alpha in mouse hepa1-6 cells and its signaling pathway.pdf,油酸对小鼠hepa1-6 细胞PGC-1α 的影响及其信号通路 研究生 王喜 导师 文芳 教授 曹仁贤 教授 中文摘要 目的:探讨油酸(Ole
particular model. These findings suggest that the PGC-1αsignaling pathwayconstitutes a viable therapeutic target for the treatment of not onlyfamilial PD, but also more common sporadic forms of the disorder. Introduction Parkin is an ubiquitin E3 ligase encoded by thePARK2gene, mutations in which...
Secondary antibodies Peptides PGC1 Peptide- #AF5395-BP Product:PGC1 Peptide Catalog:AF5395-BP Source:Synthetic Application:Blocking/Control Reactivity:Antibody available as AF5395 SizePriceInventory 1mg$350In stock Lead Time: Same day delivery ...
In conclusion, this study demonstrated that Tilianin can protect the myocardial mitochondrion in MIRI by improving mitochondrial energy metabolism and alleviating oxidative stress via regulating the AMPK/SIRT1/PGC-1α signaling pathway. AMPK is the regulatory center of many signaling pathways, in this...
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