货号:HZ501499TP用途范围:Positive Control; Immunogen; SDS-PAGE; WB 规格:10ug 50ug 100ug 200ug 1mg Recombinant Programmed Cell Death Protein 1 Ligand 1 (PDL1) Sequence Information Species:Mouse Gene ID:60553 Swiss Prot:Q9EP73 Synonyms:CD274; PDCD1LG1; B7-H; B7H1;PD-L1; PDCD1L1; PDCD1...
PD-1 gene deficiency exacerbated pancreatic injury in an experimental mouse model of AP. We observed more severe pancreatic injury in PD-1-deficient mice than in control mice, including increased pancreatic edema, inflammatory cells, infiltration, and acinar cell necrosis. We also found that PD-1...
UniProt ID: (Human) Q9NZQ7, (Mouse) Q9EP73 Entrez Gene ID: (Human) 29126, (Mouse) 60533 功能 protein binding immunoglobulin receptor superfamily 参与通路 immune response signal transduction cell surface receptor signaling pathway positive regulation of cell...
PD-L1 gene humanized MC38 cell line with Sirpa gene overexpression 品系状态 表达验证完成 *使用本品系发表的文献需注明: MC38-hPDL1/Sirpa cell line (Cat. NO. NMC-230057) was purchased from Shanghai Model Organisms Center, Inc.. 验证...
UniProt ID:(Human) Q9NZQ7,(Mouse) Q9EP73 Entrez Gene ID:(Human) 29126,(Mouse) 60533 功能 protein bindingimmunoglobulin receptor superfamily 参与通路 immune responsesignal transductioncell surface receptor signaling pathwaypositive regulation of cell migrationT cell c...
治疗方案包括: 1、手术治疗:切除肿瘤; 2、Atezolizumab(抗 PD-L1 单抗):单次剂量,用于抑制 PD-L1 通路; 3、Autogene cevumeran:个性化 mRNA 新抗原疫苗,包含最多 20 个 MHC I 类和 II 类限制性新抗原,通过静脉注射进行 8 次初始剂量和 1 次加强剂量注射; 4、mFOLFIRINOX 化疗:12个周期的化疗。 结果...
Mouse SPDL1 shRNA Plasmid的详细介绍 shRNA Plasmid to inhibit SPDL1 expression by RNA interference. This product contains 3 separate slightly different shRNA sequences which knock down mouse SPDL1 gene specifically. Each vial contains 50 μg of lyophilized shRNA. ...
Transgenic adenocarcinoma of the mouse prostate (TRAMP) is a mouse model of prostate cancer in which prostate cancers arise orthotopically because SV40 large T antigen is expressed in a prostate-restricted manner, locally downregulating the tumour suppressor molecules p53 and RB. The TRAMP-C2 cell ...
Goat Polyclonal Item No.600-101-GU8 Size:100 µg Physical State:Liquid (sterile filtered) Applications:WB, ELISA, IF Reactivity:Human, Mouse Host Species:Goat $499.00/Per Item 25 µL$125.00 100 µg$499.00 Out of stock Call for availability ...
Programmed Cell Death Protein 1(PD-1) ,一种在激活的 T 细胞上表达的受体,与其 配体 PD-L1 和 PD-L2 结合,负向调节免疫反应。 PD-1 配体存在于大多数癌症中,PD- 1:PD-L1/2 相互作用会抑制 T 细胞活性,并使癌细胞逃避免疫监视。 PD1/PDL1 信号转导通 路是肿瘤免疫抑制的重要组成部分,可以抑制 T ...