Polyamines metabolism and breast cancer: State of the art and perspectives. Breast Cancer Res. Treat. 2014, 148, 233–248. [CrossRef] [PubMed] 8. Cervelli, M.; Leonetti, A.; Cervoni, L.; Ohkubo, S.; Xhani, M.; Stano, P.; Federico, R.; Polticelli, F.; Mariottini, P.; ...
[36]. More recently, it was reported that Npnt is a potential prognostic marker in breast cancer and that Npnt mediates p38 mitogen-activated protein kinase (MAPK)–induced cell viability [38]. Npnt expression was suppressed by fibroblast growth factor (FGF)-2 via c-Jun N-terminal kinase ...
In addition, TRPC6 also acts as a negative regulator that suppresses NMDA-induced Ca2+ influx in hippocampal neurons [15], which may protect neurons from excitotoxicity in the first stages of the disease. TRPC6 overexpression has been observed in breast cancer cells [18]. Overactivation of TRPC...