ChildPediatricsLegislationEuropean UnionNon-pharmacyParacetamol is used widely in pediatrics because it has a high drug safety when used in therapeutic dosages. In case of overdose the majority of paracetamol is metabolized to N-acetyl-p-benzoquinoneimine (NAPQI), which is responsible for the severe...
What happens if I overdose?If you or your child takes too much paracetamol, get medical help or contact a Poison Control Center right away (1-800 222-1222). Quick medical attention is critical for adults and children even if they seem well....
- 《Archives of Disease in Childhood》 被引量: 41发表: 2011年 Intravenous paracetamol overdose: two case reports and a change to national treatment guidelines. Two cases of 10-fold accidental overdose with intravenous paracetamol are presented. Case 1: A 5-month-old child with intussusception ...
Given in the right dosage it is not associated with many side effects; however prolonged use may produce renal injury and massive overdose may produce hepatic injury [1]. It is the most common pharmaceutical agent involved in overdose particularly below the age of 6 years [2, 3]. There ...
Intravenous paracetamol overdose: two case reports and a change to national treatment guidelines. Case 2: A 6-month-old child received a single dose of 75 mg/kg intravenous paracetamol. The child was treated with N-acetylcysteine and remained well... Beringer,M Richard,Thompson,... - Archives...
In subject area: Pharmacology, Toxicology and Pharmaceutical Science An acute acetaminophen overdose is defined as a single ingestion of at least 7.5 g in an adult or 150 mg/kg in a child and should be considered possible in any patient who presents with a history of another overdose or alter...
in the brain, spinal cord, and gastrointestinal tract. Opioids areCNS depressantsand they block the transmission of pain messages. However, when used improperly or for recreational purposes, they can cause serious harm, including overdose and death. Opioids slow down the CNS, which in turn ...
in a 3-year-old child. Our case suggests that hepatotoxicity may occur for lower doses of IV paracetamol compared to oral ingestion, especially in the malnourished, and that a dose less than 150 mg/kg of IV paracetamol should be used to define treatment following overdose in a child with ...
Paracetamol overdose: new guidance on treatment with intravenous acetylcysteinedoi:DH999-MHRA-CON185624Venkatesan, PriyaMedicines and Healthcare products Regulatory Agency (MHRA), Market Towers, 1 Nine Elms Lane, Vauxhall, London, SW8 5NQ, UK. Telephone 020 7084 2000 (weekdays 0900 -1700), 020 ...
Treatment of paracetamol overdose.Treatment of paracetamol overdose.A letter to the editor is presented in response to the article "Reduction of Adverse Effects From Intravenous Acetylcysteine Treatment for Paracetamol Poisoning: A Randomised Controlled Trial" by D. N. Bateman, D. W. Dear, H. K....