A case of soft tissue sarcoma in a young person is described. Accident and emergency workers should be aware of this highly malignant group of tumours. Lumps in young people should not necessarily be assumed to be benign without a definite histological diagnosis....
There are increasing reports of unintentional overdose of acetaminophen (paracetamol, rINN) resulting in hepatotoxicity. To reduce this risk, the dose of acetaminophen should never exceed the maximum recommended dose, be appropriate for the weight of the patient, and reduced when risk factors for hepa...
in children.This is interesting,particularly as it is the enzyme mainly concerned with producing the toxic metabolite benzoquinoneimine during paracetamol metabolism.The reduced susceptibility of young children to paracetamol overdose has long been discussed and these findings now give a clear explanation ...
in order to relieve intense pain. Indeed, in the United States, unlike in the United Kingdom, half of the cases of overdose are apparently involuntary, with simultaneous consumption of many products containing Paracetamol for an analgesic effect [3]. Moreover, some factors could be the cause ...
The easiest way to inadvertently and massive overdose may produce hepatic injury [1]. It overdose on paracetamol is to combine various cough, cold and teething medications because people are un- * Correspondence: herbert.obu@.ng aware that paracetamol is contained in most of them [4]. 1...
4.9 Overdose Liver damage is possible in adults who have taken 10g or more of paracetamol. Ingestion of 5g or more of paracetamol may lead to liver damage if the patient has risk factors (see below). Risk Factors If the patient a) Is on long term treatment with carbamazepine, pheno...
The easiest way to inadvertently overdose on paracetamol is to combine various cough, cold and teething medications because people are unaware that paracetamol is contained in most of them [4]. Paracetamol is a weak inhibitor of the synthesis of prostaglandins. The in vivo effects of the drug ...
Paracetamol Mylan Infant Sugar Free Colour Free 120 mg/5 ml Oral Suspension should be used with caution in severe renal impairment or severe hepatic impairment. The hazards of overdose are greater in those with non-cirrhotic alcoholic liver disease. Concomitant use of other paracetamol-containing pro...
Intentional drug overdose (IDO) is the most common self-harm method among young people, with paracetamol the drug most frequently used. This study aimed to describe the characteristics, incidence, and temporal trends in paracetamol-related IDO among young people.Data from the National Self-Harm ...
However, despite the health risks associated with paracetamol overdose, consumers are often unaware of the potential toxicity [19]. For example, many parents use more than one medication at one time on a sick child without knowing what active ingredients (including paracetamol) are in each ...