Intentional drug overdose (IDO) is the most common self-harm method among young people, with paracetamol the drug most frequently used. This study aimed to describe the characteristics, incidence, and temporal trends in paracetamol-related IDO among young people.Data from the National Self-Harm ...
There are increasing reports of unintentional overdose of acetaminophen (paracetamol, rINN) resulting in hepatotoxicity. To reduce this risk, the dose of acetaminophen should never exceed the maximum recommended dose, be appropriate for the weight of the patient, and reduced when risk factors for hepa...
Since a toxic aetiology, paracetamol overdose in particular, could not be ruled out, we implemented prospective syndromic surveillance to better define the clinical characteristics of these children. To investigate risk factors, we performed a case–control study using a case definition refined during ...
From prospective data(74,77), it has been estimated that around 58000 people take paracetamol in overdose each year in England and Wales and that these episodes of poisoning prompted 3.3% of inquiries to US regionalpoisons centers(78), 10% of inquiries to the UK National Poison...
The easiest way to inadvertently and massive overdose may produce hepatic injury [1]. It overdose on paracetamol is to combine various cough, cold and teething medications because people are un- * Correspondence: herbert.obu@.ng aware that paracetamol is contained in most of them [4]. 1...
4.9 Overdose Liver damage is possible in adults who have taken 10g or more of paracetamol. Ingestion of 5g or more of paracetamol may lead to liver damage if the patient has risk factors (see below). Risk Factors If the patient a) Is on long term treatment with carbamazepine, pheno...
The easiest way to inadvertently overdose on paracetamol is to combine various cough, cold and teething medications because people are unaware that paracetamol is contained in most of them [4]. Paracetamol is a weak inhibitor of the synthesis of prostaglandins. The in vivo effects of the drug ...
A case of soft tissue sarcoma in a young person is described. Accident and emergency workers should be aware of this highly malignant group of tumours. Lumps in young people should not necessarily be assumed to be benign without a definite histological diagnosis....
Half took the overdose within an hour of first thinking of it, half (53.3%) took tablets already in the home and 58.3% bought tablets specifically for the overdose. Ten people tried to buy more than 32 tablets in one transaction; four succeeded. Most knew that a paracetamol overdose could...
Thus a barbiturate overdose should always be considered potentially life-threatening, especially for a drug abuser. In overdose a variety of signs and symptoms may be observed, depending on the drug or the combination of the drugs used; the amount of time since ingestion; and the presence of ...