Oxidative stress induced by the accumulation of reactive oxygen species (ROS) can lead to lipid, protein, nucleic acid and organelle damage, thus leading to the occurrence of cellular senescence, which is one of the core mechanisms mediating skin aging. Autophagy can maintain cellular homeostasis ...
The prevalence of aged people has increased rapidly in recent years and brings profound demographic changes worldwide. The multi-level progression of aging occurs at diverse stages of complexity, from cell to organ systems and eventually to the human as a whole. The cellular and molecular damages ...
Oxidative stress and autophagy. Oxidative stress and autophagy. Antioxidants and Redox Signaling . 2006; 8 (1-2):152–162.Kiffin R., Bandyopadhyay U., Cuervo A.M. Oxidative stress... R Kiffin,U Bandyopadhyay,AM Cuervo - 《Antioxidants & Redox Signaling》 被引量: 756发表: 2006年 Skin an...
Moreover, the interaction between oxidative stress and neuro-inflammation leads to β-amyloid (Aβ) generation in the brain of AD patients, while PD is the accumulation of degradation of dopaminergic neurons in thesubstantia nigra, due to the greater susceptibility of the nigrostriatal circuit to m...
skin agingautophagyNLR proteins.MECHANISMSMARKERSPRPBackground: Background: Ultraviolet radiation is the main cause of photoaging, which can induce oxidative stress and cellular senescence in the skin. It has been demonstrated that platelet-rich plasma (PRP) can significantly improve skin photoaging. ...
Oxidative stress is a component of many diseases, including atherosclerosis, chronic obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small molecules evaluated as antioxidants have exhibited therapeutic potential in preclini
Therefore, in order to guarantee a good level of physical well-being, in the aging process it is also proposed to counteract the effects induced by oxidative stress with different strategies. The aim of this review is to discuss the benefits deriving from a constant physical activity and by ...
Biomarkers, Oxidative Stress and Autophagy in Skin Aging. Ageing Res. Rev. 2020, 59, 101036. [Google Scholar] [CrossRef] [PubMed] Hussain, T.; Tan, B.; Yin, Y.; Blachier, F.; Tossou, M.C.B.; Rahu, N. Oxidative Stress and Inflammation: What Polyphenols Can Do for Us? Oxid....
For the past 40 years or so, oxidative stress has been increasingly recognized as a contributing factor in aging and in various forms of pathophysiology generally associated with aging. Our view of oxidative stress has been largely “superoxide-centric”, as we focused on the pathological sources ...
SCI. Activation of this pathway can effectively inhibit the oxidative stress process and promote the recovery of nerve function after SCI. Therefore, the Nrf2 pathway may be a potential therapeutic target for SCI. This review deeply analyzed the generation of oxidative stress in SCI, the role and...