These transgenic mice express the mouse alpha-chain and beta-chain T cell receptor that pairs with the CD4 coreceptor and is specific for chicken ovalbumin 323-339 in the context of I-A b. Homozygous mice are viable and fertile. In these mice there is a four-fold increase in the CD4 to...
OT-II和OT-I小鼠都是T细胞受体（TCR）转基因鼠。OT-II小鼠的CD4 T细胞可以识别OVA抗原（OVA-323-339），而OT-I小鼠的CD8 T细胞可以识别OVA抗原（OVA-257-264）。这些小鼠常被用作研究免疫反应和疫苗的模型。
回答者:网友 OT-II: (CD4+---ovalbumin 323-339 )These transgenic mice express the mouse alpha-chain and beta-chain T cell receptor that pairs with the CD4 coreceptor and is specific for chicken ovalbumin 323-339 in the context of I-A b. Homozygous mice are viable and fertile. In these ...
Previous work has established that the dendritic cells (DC) of mouse spleen regulate the IL-2 production, and hence the extent of proliferation, of the CD8... Kronin,Vadim,Hochrein,... - 《Immunology & Cell Biology》 被引量: 56发表: 2000年 H2-M3-restricted CD8+ T cells augment CD4+...
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These findings were confirmed by multiplexed staining of patient specimens and using an immune-competent mouse model of MBM. Correlation analysis across the entire immune landscape identified the presence of a rare, novel population of dendritic cells (DC3s) to be correlated with increased overall ...
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OT-II:(CD4+---ovalbumin 323-339 ) These transgenic mice express the mouse alpha-chain and beta-chain T cell receptor that pairs with the CD4 coreceptor and is specific for chicken ovalbumin 323-339 in the context of I-A b.Homozygous mice are viable and fertile.In these mice there is a...
OT-II:(CD4+---ovalbumin 323-339 )These transgenic mice express the mouse alpha-chain and beta-...
OT-II: (CD4+---ovalbumin 323-339 )These transgenic mice express the mouse alpha-chain and beta...