OT-II Mice 一、品系名称品系名称:OT-II Mice品系背景:C57BL/6J毛色:黑色相关基因型:a/a 二、品系描述T细胞是一种在免疫反应中起着关键作用的白细胞,主要有CD4+T细胞(辅助性T细胞)和CD8+T细胞(杀伤性T细胞)两种亚型。CD4+T细胞主要通过识别抗原并分泌细胞因子激活其他免疫细胞,从而协调免疫反应。与此相反,CD8+...
OT-II和OT-I小鼠都是T细胞受体（TCR）转基因鼠。OT-II小鼠的CD4 T细胞可以识别OVA抗原（OVA-323-339），而OT-I小鼠的CD8 T细胞可以识别OVA抗原（OVA-257-264）。这些小鼠常被用作研究免疫反应和疫苗的模型。
回答者:网友 OT-II:(CD4+---ovalbumin 323-339 ) These transgenic mice express the mouse alpha-chain and beta-chain T cell receptor that pairs with the CD4 coreceptor and is specific for chicken ovalbumin 323-339 in the context of I-A b.Homozygous mice are viable and fertile.In these mice...
CD86 seems to be the main costimulatory molecule involved in the proliferation response but CD80 is the main costimulatory molecule influencing cytokine secretion in pregnant mice. In conclusion, this study showed that CD80 and CD86 costimulatory molecules regulate OT-II CD4+ T lymphocyte proliferation ...
Barnden, M. J., Allison, J., Heath, W. R., & Carbone, F. R. (1998). Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunology and cell biology, 76(1), 34–40. ...
OVA specific OT-II CD4+Tcells showed reduced cytokine production and lung infiltration in OVA immunized mice.M. Akirav, EitanHenegariu, OctavianPrestonHurlburt, PaulaMarie Schmidt, AnnClynes, RaphaelC. Herold, Kevan
OVA specific OT-II CD4+Tcells showed reduced cytokine production and lung infiltration in OVA immunized mice. E M. Akirav,O Henegariu,P Prestonhurlburt,... 被引量: 0发表: 2014年 Estrogen receptor alpha (ERalpha) deficiency in macrophages results in increased stimulation of CD4+ T cells ...
aGenerally, industry and consumers do not want to deal with multiple numbers for color rendering ratings. 通常,产业和消费者不想要应付多个数字为彩色重现规定值。[translate] aWires: 2...6 per cable 导线: 2… 6每缆绳[translate] agenetic approaches in mice.[translate] ...
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Have workspace where need 2 keyboards and 2 mice with shared monitors. Able to segregate work within the small workspace with this combination and a different Logitech keyboard mouse set. Only issue is you have to press ...