Organoids and organs on a chipRecent patents relating to the manufacture and use of organoids and organs on a chip.doi:10.1038/s41587-022-01287-1Nature Publishing Group USNature Biotechnology
Organoids and organs-on-chips are two rapidly emerging 3D cell culture techniques that aim to bridge the gap between in vitro 2D cultures and animal models to enable clinically relevant drug discovery and model human diseases. Despite their similar
Organoids-on-a-chip is a newly emerging and frontier field with a marriage of organoids and microfluidic organ-on-a-chip technology. The synergistic engineering strategies can be adopted to build organ model systems in high fidelity, and to hold great potential in studies of organ development,...
SelectBIO Organoids, Spheroids and Organs-on-Chips 2024 Conferencefocuses on an important and expanding field wherein cells are being assembled using Microfluidics and Lab-on-a-Chip technologies in a functionally-relevant manner. These clusters of "assembled cells" have functional significance and can...
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Organoids and spheroids are three-dimensional (3D) cell culture models that mimic the organization and functionality of specific organs and tissues. Derived from pluripotent stem cells, iPSCs, or adult tissue stem cells, they can self-assemble and differentiate into various cell types [1]. ...
Through the miniaturization of the chip, the cost of similar organs and consumables can be saved. More importantly, the secretion factors in the micro-culture system are easy to accumulate to a higher concentration and play their functions, thus realizing the cultivation of a small number of samp...
Organoids-on-a-chip 来自 science.org 喜欢 0 阅读量: 496 作者:SE Park,A Georgescu,D Huh 摘要: Recent studies have demonstrated an array of stem cell-derived, self-organizing miniature organs, termed organoids, that replicate the key structural and functional characteristics of their in vivo ...
Organoids recreate a highly physiologically relevant system that allows researchers to investigate complex, multidimensional questions, such as disease onset, tissue regeneration, and interactions between organs. Light microscopy is an essential approach to study the complex interactions and relations with org...
Organoid models, which are three-dimensional (3D) in vitro cell culture systems that closely resemble primary tissues and organs, have the ability to recapitulate the phenotypic and genetic features of target organs [105]. However, to improve the reproducibility and scalability of cancer organoid, ...