英文别名: NUP98 (ADIR2, Nuclear Pore Complex Protein Nup98-Nup96 Precursor, NUP196) (AP)中文名: 中文别名: CBNumber: CB04929671 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 NUP98 (ADIR2, Nuclear Pore Complex Protein Nup98-Nup96 Precursor, NUP196) (AP)化学...
The nuclear pore complex (NPC) is a macromolecular protein assembly embedded in the double lipid bilayer of the nuclear membrane, and is the sole gateway of macromolecular traffic between the nucleus and cytoplasm. The NPC serves as a barrier to inhibit the free molecular flux in and out of ...
Nuclear Pore Complex ProteinsPolyproteinsProtein IsoformsRecombinant ProteinsProtein Processing, Post-TranslationalThe vertebrate nucleoporin Nup98 can be expressed in two distinct forms from differentially spliced mRNAs, either as a 98-kDa protein or as the 195-kDa Nup98/Nup96 polyprotein. Both forms...
A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm. Cell 72, 29–38 (1993). Article CAS PubMed Google Scholar Powers, M. A., Forbes, D. J., Dahlberg, J. E. & Lund, E. The vertebrate GLFG nucleoporin, Nup98, is an essential ...
S. Protein import through the nuclear pore complex is a multistep process. J. Cell Biol. 109, 971–982 (1989). CAS PubMed Google Scholar Nachury, M. V. & Weis, K. The direction of transport through the nuclear pore can be inverted. Proc. Natl Acad. Sci. USA 96, 9622–9627 (...
The expression of Nup98 was upregulated and that of the Nup88 protein was downregulated in U937 cells treated with deguelin. Conclusion: Deguelin is able to inhibit the proliferation of U937 cells by regulating the cell cycle such that cells are arrested at the S and G2/M phases, so that...
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The antitumor effects of deguelin are related to upregulating the expression of Nup98 and downregulating the expression of Nup88 protein in U937 cells. 展开 关键词: deguelin U937 cells nucleoporin Nup98 Nup88 DOI: CNKI:SUN:ZGLL.0.2005-10-019 年份: 2005 ...
Nuclear pore complex protein Nup98 (315-360) 是核孔复合物 (NPC) 蛋白的 315-360 片段部分。 公司简介 武汉科斯坦生物科技有限公司是一家致力于前沿生物技术研发与成果转化的创新型高科技企业。 公司成立以来,一直专注于生命科学研发与技术服务领域,与 高校建立合作关系,逐步建立并完善了“分离纯化平台”、“分析...
Two multiprotein complexes, the 10-member Y complex (named because of its shape) and the five-member Nup93 complex make up the scaffold of the pore. The cytoplasmic and nuclear rings are assembled from 16 copies each of the Y complex. The Nup93 complex forms the framework of the spoke ...