doi:10.1016/0167-7799(87)90081-3Iain D. CampbellBrian SheardElsevier LtdTrends in BiotechnologyI. D. Campbell and B. Sheard, "Protein structure determination by NMR," Trends in Biotechnology, vol. 5, no. 11, pp. 302-306, 1987.
Solid-state NMR spectroscopy of uniaxially oriented planar bilayer lipid samples is ideally suited for this purpose. This article outlines the methodology for membrane protein structure determination using solid-state NMR of oriented planar lipid bilayer samples. Recent developments in sample preparation, ...
Targeting of proteins for structure determination in structural genomic programs often includes the use of threading and fold recognition methods to exclude proteins belonging to well-populated fold families, but such methods can still fail to recognize preexisting folds. The authors illustrate here a ...
Protein structure determination by high-resolution solid-state NMR spectroscopy: application to microcrystalline ubiquitin. High-resolution solid-state NMR spectroscopy has become a promising method for the determination of three-dimensional protein structures for systems which ... Stephan G.Zech,A.Joshua ...
protein structure determination by NMRdistance geometrystructure calculation with DIANAmolecular dynamics simulationThe NMR solution structure of bovine pancreatic ... KD Berndt,PG And,K Wüthrich - 《Proteins Structure Function & Bioinformatics》 被引量: 133发表: 1996年 Improving the accuracy of NMR st...
An approach for high-throughput structure determination of proteins by NMR spectroscopy An approach is described for rapidly determining protein structures by NMR that utilizes proteins containing 13 C-methyl labeled Val, Leu, and Ile (未1) an... A Medek,ET Olejniczak,RP Meadows,... - 《Journa...
{NMR} structure determination of proteins and protein complexes larger than 20 {kDa} {[In} Process Citation] Activity screening and insertional inactivation of lipopolysaccharide (LPS) biosynthetic genes in Helicobacter pylori have led to the successful characteri... GM Clore,AM Gronenborn 被引量:...
Simultaneously, problems of sensitivity loss due to larger linewidths associated with the increase of molecular weights has been solved by use of large three-dimensional NMR/protein structure/triple-resonance NMR/stable isotope关键词: three-dimensional NMR protein structure triple-resonance NMR stable ...
Protein structure determination in solution by NMR spectroscopy. The introduction of nuclear magnetic resonance (NMR) spectroscopy as a second method for protein structure determination at atomic resolution, in addition ... K Wüthrich - 《Journal of Biological Chemistry》 被引量: 245发表: 1990年 NMR...
The protein contains paramagnetic copper(II), whose electronic relaxation times are quite unfavorable for NMR solution st... I Bertini,S Ciurli,A Dikiy,... - 《Journal of the American Chemical Society》 被引量: 191发表: 2001年 Breaking symmetry in the structure determination of (large) ...