ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "...
Structure determination is a procedure by which the three-dimensional atomic coordinates of a molecule or biomolecule are solved using an analytical technique. Many techniques are used in structure determination, most commonly X-ray crystallography, NMR spectroscopy, electron microscopy and molecular modelli...
In the last decade NMR spectroscopy has proven to be an invaluable tool for determining solution structures of medium sized macromolecules. Advances in magnet technology and electronic data...doi:10.1007/978-3-642-77798-1_1J. A. C. Rullmann...
Membrane protein structure determination using solid-state NMR. Solid-state NMR is emerging as a method for resolving structural information for large biomolecular complexes, such as membrane-embedded proteins. In princ... A Watts,SK Straus,SL Grage,... - 《Methods Mol Biol》 被引量: 63发表:...
This chapter reviews the methodologies for RNA structure determination by liquid-state nuclear magnetic resonance (NMR). The routine production of milligram quantities of isotopically labeled RNA remains critical to the success of NMR-based structure studies. The standard method for the preparation of is...
Purchase Organic Structure Determination Using 2-D NMR Spectroscopy - 2nd Edition. Print Book & E-Book. ISBN 9780123849700, 9780123849717
NMR-based RNA structure determinationRNA structure determination can be performed by liquid state nuclear magnetic resonance (NMR) spectroscopy that requires millimolar amounts of isotopically labeled RNA to obtain well-resolved signals. A successful approach to generate sufficient isotopically labeled RNA ...
Automated methods for NMR structure determination of proteins are continuously becoming more robust. However, current methods addressing larger, more complex targets rely on analyzing 6–10 complementary spectra, suggesting the need for alternative appro
The next two chapters present RNA structure determination using NMR spectroscopy (described by E. Puglisi and J. Puglisi) and X-ray crystallography (described by S. Holbrook). Both chapters explain the basics such that a first year ... Pan,Tao - 《Nature Structural & Molecular Biology》 被引...
much too large for NOE-based structure determination, but they still fall under the domain of solution-state NMR and can be useful in certain ... GD Henry,BD Sykes - 《Methods in Enzymology》 被引量: 373发表: 1994年 The use of pseudocontact shifts to refine solution structures of paramagn...