Wuthrich K: The way to NMR structures of proteins. Nat Struct Biol 2001, 8(11):923-5.Wuthrich, K. (2001) Nature Struct. Biol. 8, 923-925. The way to NMR structures of pro- teins.Kurt Wuthrich (2001), The way to NMR structures of proteins. Nature Structural Biology 8, 923-925....
and Gronenborn, A M.: Determining the structures of large proteins and protein complexes by NMR. Trends Biotechnol. 16, 22-34, 1998. :... GM Clore,AM Gronenborn - Springer US 被引量: 304发表: 2002年 Recommendations for the presentation of NMR structures of proteins and nucleic acids. ...
Figure 1. Illustrating the spectrum of AI-based strengths in characterizing protein structure and dynamics along with the high complementarity of NMR spectroscopy (A–E) AI methods have achieved remarkable success in predicting the structures of small proteins (A) and occasionally in predicting protein...
Protein solubility and stability depend on the co-solutes present. There is little theoretical basis for selection of suitable co-solutes. Some guidance is provided by the Hofmeister series, an empirical ordering of anions according to their effect on so
We present a method that measures the accuracy of NMR protein structures. It compares random coil index [RCI] against local rigidity predicted by mathematical rigidity theory, calculated from NMR structures [FIRST], using a correlation score (which asses
Nuclear magnetic resonance (NMR), and its imaging counterpart, magnetic resonance imaging (MRI), provide a suitable way to non-invasively assess plant water status throughout the plant’s life cycle, and portable devices offer the possibility of taking measurements in a plant’s natural environment...
Wüthrich’s research group has solved some 50 protein structures this way, including protein complexes of tendamistat, an amylase inhibitor, metallothionein, a protein that transports metals, and prion proteins. Protein NMR has moved on apace since those early days and current estimates suggest tha...
Indeed, other membrane proteins serve as channels for water and ions, creating microenvironments by which polar and charged species can pass through the membrane without directly encountering the hydrophobic tails of membrane lipids. The first crystal structures of i-CLiPs, of rhomboids [1], [2]...
Specifically, we assume that the energetic parameters will be a function on the fraction of bases C or G in the DNA sequence, which may change in a significant way the thermal stability of the duplex. This description will be primarily of interest for the PCR pairing statistics, since it ...
et al. Structure of the TPR domain of p67phox in complex with Rac·GTP. Mol. Cell 6, 899–907 (2000). Article CAS PubMed Google Scholar Ogura, K. et al. NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide. ...