The invention discloses an NKX3.1 (the human NK-3 prostate specific gene) gene mutation detection liquid chip and specific primers. The liquid chip mainly comprises the following parts: each ASPE primer contains a tag sequence at the 5' terminal and a specific primer sequence aiming at target...
基因又名: BCH,BHC,NK-2,NKX2.1,NKX2A,NMTC1,T/EBP,TEBP,TITF1,TTF-1,TTF1 Gene ID: 7080 种属 Homo sapiens 基因序列编号: NM_001079668.3 基因描述 Homo sapiens NK2 homeobox 1 (NKX2-1), transcript variant 1, mRNA DNA编码区: atgtggtccggaggcagtgggaaggcgcggggctgggaggccgcggcgggagggaggagc ...
Gene Name NKX3-1 Accession No. Q99801 P97436 Alternate Names NKX3-1; NKX3.1; NKX3A; Homeobox protein Nkx-3.1; Homeobox protein NK-3 homolog A Description NK3 homeobox 1(NKX3-1) Homo sapiens This gene encodes a homeobox-containing transcription factor. This transcription factor functions as...
A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer re...
Gene SummaryThis gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation. ...
and NKX 2 .5 gene analysis in C hinese U ygur pat ie nts with conge nital heart disease [J ] . Chin Med,200 9 ,122 ( 4 ) :4 16—4 l 9. [6] Herceg z .Epigenetics and cancer:towards an ev alua tion of the impa ct ...
NKX6-1 gene / cDNA is a protein-coding gene which located on 4q21.23. The NKX6-1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, and frog.180 organisms have orthologs with human gene NKX6-1.
linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube ...
Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing ...
abilityofthevnd/NK 一2homeoproteintoregulategeneexpression: Treansgenicalterationsandtertiarystructure.ProcNailAcadSci USA,2003;l00:31l9 11McElhinneyDB,GeigerE,BlinderJ,et01.NKX2.5mutationsin patientswithcongenitalheartdiease.JAmCoilCardio1.2003;42: ...