The function of Nkx2-1 as a proto-oncogene was recently characterized and the gene is implicated as a contributory factor in lung cancer development. In this review, we summarize the role of this transcription factor in the development, diagnosis, and prognosis of lung cancer in the hope of ...
基因又名: BCH,BHC,NK-2,NKX2.1,NKX2A,NMTC1,T/EBP,TEBP,TITF1,TTF-1,TTF1 Gene ID: 7080 种属 Homo sapiens 基因序列编号: NM_001079668.3 基因描述 Homo sapiens NK2 homeobox 1 (NKX2-1), transcript variant 1, mRNA DNA编码区: atgtggtccggaggcagtgggaaggcgcggggctgggaggccgcggcgggagggaggagc ...
NKX2-1(NKXhomeobox-1gene,NKX同源框-1基因)是NKX2基因家族的含 有同源结构域的转录因子,其表达于人类胚胎肺和成年肺中,以维持肺的正常发育 及功能。有研究认为,NKX2-1可能是肺癌的一个驱动核心[9-10],是肺腺癌 特异性的生物指标。临床研究认为,NKX2-1可作为判断肺腺癌的组织来源 [11],以及肺源性恶性间...
提供的TK1单克隆抗体(M06), 克隆号3E2产品为小鼠源单克隆抗体,对应的抗体亚型为IgG2b Kappa。该基因又称TK2,全名为thymidine kinase 1, soluble。对应Gene号为BC007986,其蛋白编号为AAH07986.1。 应用类型 S-ELISA,ELISA,WB-Re,WB-Tr 免疫原 真核无细胞体系表达的人源TK1全长或部分序列蛋白作为免疫原。与大...
This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. Applications: ELISA, WB Name of antibody: NKX2-1 Immunogen: Synthetic peptide of human NKX2-1 Full name: NK2 homeobox 1 Synonyms: BCH, BHC, ...
[K ey w ords]NKX2-1 gene;SFTPC gene;gene mutation;neonatal respiratory failure N K X同源框-1CNKX2-1)，又称甲状腺转录因子-1 (TTF-1)，位于染色体14ql3区带，由3个外显子和2个内 含子组成。编码一个转录因子，对甲状腺、肺和前脑腹侧的分化和形态的发生有重要作用。1病例资料 患儿，女，1M2D。
This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. 参考效价: Western blotting: 1:100-400 Immunocytochemistry in fixed cells: 1:100-500 Immunohistochemistry in frozen section: 1:100-500 ...
TTF1; NKX2A; NMTC1; T/EBP; TITF1; TTF-1; NKX2.1 相关类别: 一抗 储存: 冷冻(-20℃) 宿主: Mouse 抗原: NKX2-1 反应种属: Human 标记物: Unconjugate 克隆类型: mouse monoclonal 技术规格 Background: This gene encodes a protein initially identified as a t hyroid-specific transcription fact...
NKX2-1 gene is targeted by H19 lncRNA and is found to be overexpressed in benign nodular goiter tissues 来自 SciELO 喜欢 0 阅读量: 2 作者: SM Javadirad 摘要: Objective: Nodular goiter may increase the risk of thyroid cancer, but the genetic factors contributing to nodular goiter are ...
lung development and surfactant homeostasis. Mutations and deletions in this gene are associated with benign hereditary chorea, congenital hypothyroidism, neonatal respiratory distress, and may be associated with thyroid cancer. NKX2-1 has been suggested to be a candidate suppressor of malignant ...