Strategies to amplify NKG2D-mediated antitumor responses and counteract tumor immune escape mechanisms will be discussed.doi:10.1038/onc.2008.272Nausch, NCerwenka, AOncogeneNausch N, Cerwenka A: NKG2D ligands in tumor immunity. Oncogene. 2008, 27 (45): 5944-5958. 10.1038/onc.2008.272...
[2] Nausch, N., Cerwenka, A. NKG2D ligands in tumor immunity. Oncogene 27, 5944–5958 (2008). https://doi.org/10.1038/onc.2008.272 [3]Yu-Hsiang Chang, John Connolly, Noriko Shimasaki, Kousaku Mimura, Koji Kono and Dario Ca...
γδ+and CD8+T-cell-mediated immune response to tumors. Ligands for NKG2D are rarely detectable on the surface of healthy cells and tissues, but are frequently expressed by tumor cell lines and in tumor tissues. It is evident that the expression levels of these...
ULBPs, human ligands of the NKG2D receptor, stimulate tumor immunity with enhancement by IL-15 [J]. IMMUNOBIOLOGY. 2016, 108 (4):1313-1319.[10] Roile A, Mousavi-JaziM, Eriksson M,et al. Effects of human cytomegalovirus infection on ligands for the activating NKC2D receptor of NK cells...
[16] Sutherland, Claire L., et al. "ULBPs, human ligands of the NKG2D receptor, stimulate tumor immunity with enhancement by IL-15." Blood 108.4 (2006): 1313 -1319.[17] Morgado, Sara, et al. "NK cell recognition and killing of melanoma cells is controlled by multiple activating ...
"ULBPs, human ligands of the NKG2D receptor, stimulate tumor immunity with enhancement by IL-15." Blood 108.4 (2006): 1313 -1319.[17] Morgado, Sara, et al. "NK cell recognition and killing of melanoma cells is controlled by multiple activating receptor-ligand interactions." Journal of innat...
OPEN Oncogene (2017) 36, 933–941 www.nature.com/onc ORIGINAL ARTICLE CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells M Sauer1,5, M Schuldner1,5, N Hoffmann1, A Cetintas1, KS Reiners1, O Shatnyeva1, M Hallek1,2, HP Hansen1, S Gasser3 and EP...
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity. 2008;28(4):571–80. Article PubMed CAS Google Scholar Hedlund M, Stenqvist AC, Nagaeva O, Kjellberg L, Wulff M, Baranov V, et al. Human placenta expresses and secretes NKG2D ligands via...
Enhanced translation of NKG2D ligands in tumor cells expressing hyperactivated RAS is expected to activate immune cells and may provide a barrier against tumori- genesis. In summary, NKG2D ligands expression may be a consequence of the activation of several oncogenic signaling pathways, in...
Citation:Wan J, Li GH. Advances in understanding the role of NKG2D and its ligands in digestive system tumors.Shijie Huaren Xiaohua Zazhi2009; 17(31): 3233-3236 https://www.wjgnet.com/1009-3079/full/v17/i31/3233.htm 0 引言 NKG2D(natural killer group 2D)是20世纪90年代发现的免疫受体,...