chemiluminescence imaginginflammation tracingNIR-II imagingChemiluminescence (CL) sensing without external excitation by light and autofluorescence interference has been applied to high-contrast in vitro immunoassays and in vivo inflammation and tumor microenvironment detection. However, conventional CL sensing ...
and fetal bovine serum (FBS) and exhibited the excellent biological stability, indicating the potential for furtherin vivo application. To study the NIR-II fluorescence characters, we firstly detected the maximum imaging depth of BDT-TTQ NPsin vitro and the penetration depth can achieve 6 mm at ...
Fluorescence imaging in the second near-infrared window (NIR-II) holds promise for real-time deep tissue imaging. In this work, we design a low-band gap conjugated polymers(pTB) with donor-acceptor (D-A) structures by Stille cross-coupling reaction, which can improve the quality of fluorescen...
Owing to reduced light scattering and tissue autofluorescence, in vivo fluorescence imaging in the 1,000–3,000-nm near-infrared II (NIR-II) spectral range can afford non-invasive imaging at depths of millimetres within biological tissue. Infrared fluorescent probes labelled with antibodies or other...
The in vitro and in vivo observation data indicated that iRFPs could serve as fluorescent protein probes for long-duration NIR-II imaging (at least 15 months). Furthermore, to achieve tissue-specific and controlled expression of this probe, we generated inducible iRFP713 transgenic mice with ...
Fluorescence imaging in the second near-infrared window (NIR-II, 900–1880nm) with less scattering background in biological tissues has been combined with the confocal microscopic system for achievi...
Moreover, the TPSe NPs demonstrate their photothermal ablation of cancer cells in vitro and tumor in vivo with the guidance of NIR-II imaging. It is worth noting that the TPSe NPs have good biocompatibility without obvious side effects. Thus, this work provides new insight into the ...
该成果以“Near-Infrared-II Fluorescent Probes for Analytical Applications: From In Vitro Detection to In Vivo Imaging Monitoring”为题发表于Account of Chemical Research 论文信息 Sha Liu, Wenhong Dong, Hui-quan Gao*, Zhaorui Song*, Zhen Cheng*. Near-Infrared-II Fluorescent Probes for Analytical ...
The NIR-II images were acquired from an in vivo optical NIR-II imaging system built by Suzhou NIR-Optics Technologies Co., Ltd. 2.4. Photothermal performance and photostability The in vitro photothermal performance of CH4T@MOF-PEG-AE was measured by irradiating the solution with 808 nm laser ...
vitro. With the help of long-wavelength emission (>1000 nm), the imaging depth is 6 mm, far exceeding the traditional near-infrared region (NIR-I) reagents. Under 808 nm laser irradiation, the high-resolution second near-infrared window (NIR-II) fluorescence imaging of healthy mouses’ ...