本研究可以为NIR-II荧光成像引导的有效GBM治疗提供一种具有累积治疗作用的多功能治疗纳米平台。图1. 成像引导下原位GBM光热NO免疫治疗的纳米诊疗方案 在这项研究中，构建了一种基于半导体聚合物（SP）的纳米治疗平台，将其用于NIR-II荧光成像引导的原位GBM光热NO免疫治疗。中性粒细胞靶向配体唾液酸（SA）共价连接到纳米...
胶质母细胞瘤(GBM)是最致命的原发性脑肿瘤之一,但其诊断和治愈性治疗仍然是一个巨大的挑战。2024年8月19日,东华大学李静超团队在Advanced Science在线发表题为“Neutrophil-Targeting Semiconducting Polymer Nanotheranostics for NIR-II Fluorescence Imaging-Guided Photothermal-NO-Immunotherapy of Orthotopic Glioblastoma”...
由于人体比小鼠的腹膜空间更大,故而将内窥镜或腹腔镜用于人体的可操作性更强,因此,该技术有望扩展到使用腹腔镜、支气管镜、胸腔镜或膀胱镜等将光纤扩散器放置在肿瘤内或附近,并用于临床肿瘤的治疗。 Figure 6 Multi-color fluorescence endoscopic system and NIR- Figure 6 Multi-color fluorescence endoscopic syste...
由于人体比小鼠的腹膜空间更大,故而将内窥镜或腹腔镜用于人体的可操作性更强,因此,该技术有望扩展到使用腹腔镜、支气管镜、胸腔镜或膀胱镜等将光纤扩散器放置在肿瘤内或附近,并用于临床肿瘤的治疗。 Figure 6 Multi-color fluorescence endoscopic system and NIR- Figure 6 Multi-color fluorescence endoscopic syste...
良好的生物相容性和溶酶体靶向的抗肿瘤光疗，展示了精确鼻咽癌治疗诊断学的范式。参考文献 Li Z, Yang S, Xiao H, et al. Lysosome-Targeted and pH-Activatable Phototheranostics for NIR-II Fluorescence Imaging-Guided Nasopharyngeal Carcinoma Phototherapy[J]. Bioconjugate Chemistry, 2024.
Xiao, P.; Sun, Y.; Liang, M.; Yang, S.; Li, J.; Zhang, L. e.; Jiang, X.; Wu, W., A fluorophore with dithienopyrrole donor for beyond 1300 nm NIR-II fluorescence/photoacoustic dual-model imaging and photothermal therapy. Materials Today Nano 2023, 24. ...
该研究成果题为“NIR-II Fluorescence Imaging-guided Oxygen Self-sufficient Nano-platform for Precise Enhanced Photodynamic Therapy”。首次提出NIR-II荧光引导下增强乏氧肿瘤的光动力治疗(PDT)策略。团队研究生李文玲为文章的第一作者,田梗...
参考文献 Peng, L.; Liu, Y.; Zhang, J.; Zhang, Z.; Liu, Z.; Fang, X.; Wang, Y.; Wu, C., Surface Plasmon-Enhanced NIR-II Fluorescence in a Multilayer Nanoprobe for Through-Skull Mouse Brain Imaging. ACS Appl Mater Interfaces 2022, 14 (34), 38575-38583.
This article has beenupdated Abstract Owing to reduced light scattering and tissue autofluorescence, in vivo fluorescence imaging in the 1,000–3,000-nm near-infrared II (NIR-II) spectral range can afford non-invasive imaging at depths of millimetres within biological tissue. Infrared fluorescent pr...
Li Z, Yang S, Xiao H, et al. Lysosome-Targeted and pH-Activatable Phototheranostics for NIR-II Fluorescence Imaging-Guided Nasopharyngeal Carcinoma Phototherapy[J]. Bioconjugate Chemistry, 2024. ⭐️ ⭐️ ⭐️ 动物活体荧光成像系统 - MARS ...