Fluorescence imaging in the second near-infrared window (NIR-II) holds promise for real-time deep tissue imaging. In this work, we investigated the NIR-II fluorescence properties of a liposomal formulation of i
2024年8月19日,东华大学李静超团队在Advanced Science在线发表题为“Neutrophil-Targeting Semiconducting Polymer Nanotheranostics for NIR-II Fluorescence Imaging-Guided Photothermal-NO-Immunotherapy of Orthotopic Glioblastoma”的研究论文。该研究报道了中性粒细胞靶向半导体聚合物纳米治疗剂(SSPNiNO)用于小鼠模型中原位胶质...
IRFEM 旨在实现荧光、热量和 ROS 生成能力的平衡，因此使其成为 NIR-II 成像引导的 PTT/PDT 联合治疗的理想候选者。制备的IRFEM@DHP可以通过增强渗透性和保留率（EPR）效应在鼻咽癌细胞中富集，然后倾向于在酸性溶酶体中积累以释放IRFEM。之后，IRFEM可以通过大量的吗啉特异性靶向溶酶体，并在光照射下产生大量的热...
与此同时,四硫键与MnO2也会发挥协同作用以消耗谷胱甘肽,从而进一步增强CDT的细胞杀伤效果。 Ziliang Zheng. et al. Biodegradable Silica-Based Nanotheranostics for Precise MRI/NIR-II Fluorescence Imaging and Self-Reinforcing Antitumor Therapy. Small. 2021 DOI: 10.1002/smll.202006508 https://onlinelibrary.wiley...
Lysosome-Targeted and pH-Activatable Phototheranostics for NIR-II Fluorescence Imaging-Guided Nasopharyngeal Carcinoma Phototherapy[J]. Bioconjugate Chemistry, 2024. ⭐️ ⭐️ ⭐️ 动物活体荧光成像系统 - MARS In Vivo Imaging System 高灵敏度 - 采用深制冷相机,活体穿透深度高于15mm 高分辨率 - ...
NIR-II fluorescence lifetime imaging system 本文利用NIR-II-LT完成了小鼠活体肝脏和胃的荧光寿命成像实验。NIR-II-LT是一款长荧光寿命(微秒-毫秒)成像的近红外二区系统,用于表征体内或体外探针的荧光寿命信息。搭载深度制冷的InGaAs近红外相机能够满足长时间曝光成像,尤其对于弱光能有很高的采集效率。自主开发的荧光...
Y. Yang, C. Cen, L. Kan, Q. Zhao, Z. Huang, S. Li. Organic probes for three-photon fluorescence imaging in NIR-II window: Design, applications, and perspectives.Interdiscip. Mater.2025; 4(1): 109-137. doi: ...
目前，这是首次使用聚合物纳米诊疗平台，在NIR-II荧光成像引导的原位GBM PTT-NO-免疫治疗中的开创性研究。参考文献 Liu J, Cheng D, Zhu A, et al. Neutrophil゛rgeting Semiconducting Polymer Nanotheranostics for NIR㊣ Fluorescence Imaging﹗ided Photothermal㎡﹎munotherapy of Orthotopic Glioblastoma[J]. ...
Liu J, Cheng D, Zhu A, et al. Neutrophil‐Targeting Semiconducting Polymer Nanotheranostics for NIR‐II Fluorescence Imaging‐Guided Photothermal‐NO‐Immunotherapy of Orthotopic Glioblastoma[J]. Advanced Science, 2024: 2406750. ⭐️ ⭐️ ⭐️ ...
While second near-infrared (NIR-II) fluorescence imaging is a promising tool for real-time surveillance of surgical operations, the previously reported organic NIR-II luminescent materials for in vivo imaging are predominantly activated by expensive lasers or X-ray with high power and poor illuminatio...