Bai, L.; Hu, Z.; Han, T.; Wang, Y.; Xu, J.; Jiang, G.; Feng, X.; Sun, B.; Liu, X.; Tian, R.; Sun, H.; Zhang, S.; Chen, X.; Zhu, S., Super-stable cyanine@albumin fluorophore for enhanced NIR-II bioimaging. Theranostics 2022, 12 (10), 4536-4547. ⭐️ ...
NIR-II成像的高灵敏度可对肿瘤组织进行精准定位。利用靶向NIR-II荧光探针成像并引导进行小鼠头部肿瘤切除手术。实验分两组进行,在完全切除手术后(左二),选区线扫结果显示病灶部位近红外信号明显减弱,与健康组织相似,在对比实验(右二,人为留下少部分肿瘤组织)中则观察到部分区域仍存在高强度信号,肿瘤组织的切除并不完...
展示了呋喃在构建高性能NIR-II荧光探针方面的潜力，为生物成像领域提供了一种新型的D单元选择，并为肿瘤诊断和治疗提供了一种有效的工具。参考文献 Liu, C., Li, M., Ma, H., Hu, Z., Wang, X., Ma, R., et al. (2023). Furan Donor for NIR-II Molecular Fluorophores with Enhanced Bioimaging P...
体内代谢行为可以间接反映花菁@BSA的光稳定性特征。最后进行淋巴结成像以评估NIR-II成像能力。使用三种花菁@BSA（IR-780@BSA，IR-808@BSA，IR-783@ BSA）和临床使用的ICG研究了淋巴结成像的光稳定性。IR-780@BSA在四个测试探针中仍然最稳定（Figure 6G）。IR-780@BSA（1 mM，25 μL）为腘窝淋巴结可视化提供...
本文要点:具有第二近红外(NIR-II)发射的分子荧光团由于其优异的生物相容性和高分辨率,在深层组织生物成像方面具有巨大的潜力。最近,J-聚集被用于构建长波长NIR-II发射器,因为它们的光带在形成水分散性纳米聚集体时显示出显著的红移。然而,由于J型主链的种类有限和严重的荧光猝灭,它们在NIR-II荧光成像中的广泛应用受...
A NIR-II-Emissive Organic Nanomedicine with Biomimetic Engineering for High-Contrast Targeted Bioimaging and Multiple Phototherapies of Pancreatic Tumors Yiwei Wang#,Jie Zhang#,Yu Wang*, Jie Yu, Yijian Gao, Yuliang Yang, Xiliang Li, Hongcheng Wang*, Shengliang Li* ...
Bai, L.; Hu, Z.; Han, T.; Wang, Y.; Xu, J.; Jiang, G.; Feng, X.; Sun, B.; Liu, X.; Tian, R.; Sun, H.; Zhang, S.; Chen, X.; Zhu, S., Super-stable cyanine@albumin fluorophore for enhanced NIR-II bioimaging. Theranostics 2022, 12 (10), 4536-4547. ...
In the NIR-II fluorophore, small organic molecule fluorophore has attracted much attention because of its good biocompatibility and good pharmacokinetic properties. In this review, we briefly introduced the existing NIR-II organic small molecule fluorophores, and introduced the existing relatively mature ...
Ming-Ho Liu. et al. Polymethine-Based Semiconducting Polymer Dots with NarrowBand Emission and Absorption/Emission Maxima at NIR-II for Bioimaging. Angewandte Chemie International Edition. 2020 DOI: 10.1002/anie.202011914 https://onlinelibrary.wiley.com/doi/10.1002/anie.202011914 ...
针对上述问题,苏州大学李盛亮教授与香港城市大学李振声教授、罗敬东教授合作,在Advanced Materials上发表了题为“Neutral Cyanine: Ultra-Stable NIR-II Merocyanines for Highly Efficient Bioimaging and Tumor-Targeted Phototheranostics.”的研究论...