NIR-II laserPlasmonic Cu9S8Photo-Fenton-like reactionImmunogenic cell deathImmunotherapyChemodynamic therapy (CDT) is typically used to modulate the immunogenic tumor microenvironment and extend the benefits of immune checkpoint therapy because of its good tumor selectivity. However, the poor catalytic ...
(A) NIR photothermal enhanced chemotherapy mechanism of GIAN/DOX;(B) UV-Vis characterization of the DOX-loaded GIANs;(C)cell viability of MCF-7 cells with and without NIR laser irradiation after incubation with free DOX,GIAN,and GIAN/DOX,respectively. Adapted with permission from Ref.[23]. ...
Fig. 10 Infrared thermal images of the mice treated with saline(A) and gemcitabine/polypyrrole composite NPs (B) under the irradiation of 808 nm laser at the power density of 1 W/cm2 after 0, 2, 4, 8 and 16 min 化疗药物的大量释放,因此对肿瘤生长的影响十分有限. 由图10(B)可见,尾静脉...
相比之下,几乎所有NPs+激光组的细胞都表现出红色荧光,显示出Y16-Pr-PEG NPs在NIR-II激光辅助下具有优异的协同治疗效果。用PBS,PBS +激光或NPs处理后,4T1细胞的细胞骨架仍然显示出均匀且分布良好的形态,而NPs +Laser组具有细胞骨架丝解聚导致的明显的丝状细胞结构片段(Figure 4c(ii))。从Figure 4c(iii)中可以清...
用PBS,PBS +激光或NPs处理后,4T1细胞的细胞骨架仍然显示出均匀且分布良好的形态,而NPs +Laser组具有细胞骨架丝解聚导致的明显的丝状细胞结构片段(Figure 4c(ii))。从Figure 4c(iii)中可以清楚地看出,所有对照组对细胞增殖没有明显影响,而NPs+激光可通过DNA合成抑制对细胞增殖有明显影响。
different power densities (a) 0.50 W/cm2; (b) 0.75 W/cm2and (c) 1 W/cm2of 730 nm laser irradiation; (d) The intensity changes of the absorption peak of DPBF under irradiation with different powers; (e) Absorption spectra of DPBF solution treated with NIR laser (730 nm, 1 W/cm2...
图1. 典型频率梳的时域和频域。发表于 J. Hecht,“频率梳走向大众”,Laser Focus World,48, 1, 103–108(2012 年 1 月)。 德克萨斯农工大学的研究人员在Hans A. Schuessler 教授的带领下,最近采用普林斯顿仪器公司的科学 InGaAs 相机,通过简单的实验装置在近红外区域进行飞秒频率梳游标光谱分析1。他们的创新工作...
最近开发的基于飞秒频率梳的技术(见图 1)可用于各种先进测量应用，包括高精度光谱、原子钟、化学传感器、超级激光器、长距离通信和激光雷达。图 1. 典型频率梳的时域和频域。发表于 J. Hecht，“频率梳走向大众”，Laser Focus World，48, 1, 103–108(2012 年 1 月)。德克萨斯农工大学的研究人员在Hans A. ...
接下来，将4T1荷瘤小鼠随机分为三组：PBS + Laser，仅BHcy-NPs和BHcy-NPs + Laser。注射PBS或BHcy-NPs（0.5mg kg）后−1，500μm，30μL），将肿瘤暴露于808 nm激光（0.25Wcm−2）和体内光热图像由热像仪监测。与“PBS+激光”组相比，“BHcy-NPs+激光”组的肿瘤温度在用808nm光照射10分钟后迅速...
Xu Y, Zhang Y, Li J,et al. NIR-II emissive multifunctional AIEgen with single laser-activated synergistic photodynamic/photothermal therapy of cancers and pathogens. Biomaterials. 2020 Nov;259:120315. doi: 10.1016/j.biomaterials.2020.120315. Epub 2020 Aug 15. PMID: 32836057. ...