YIN H Y,ZHAO C L,YOU H Z,et al.Mild ketone formation via Ni-catalyzed reductive coupling of unactivated alkyl halides with acid anhydrides[J].Chem Commun,2012,48:7034-7036.Yin, H., Zhao, C., You, H., Lin, K. & Gong, H. Mild ketone formation via Ni- catalyzed reductive coupling...
Mild ketone formation via Ni-catalyzed reductive coupling of unactivated alkyl halides with acid anhydridesYinH.ZhaoC.YouLinK.GongingentaconnectChemical Communications Royal Society of ChemistryYIN H Y,ZHAO C L,YOU H Z,et al.Mild ketone formation via Ni-catalyzed reductive coupling of unactivated ...
O643 ReactionMechanismfortheNi-CatalyzedReductiveCross-Couplingof ArylHalides JIANGFengRENQing-Hua * (DepartmentofChemistry,CollegeofScience,ShanghaiUniversity,Shanghai200444,P.R.China) Abstract:ThemechanismoftheNi-catalyzedreductivecross-couplingreactionofbromobenzene(R1)and methyl4-bromobenzoate(R2)toforman...
In summary, we have identified a practical approach for the preparation of β,γ-unsaturated carbonyl compounds, by nickel-catalyzed reductive coupling of two easily accessible C–O electrophiles. The method displayed good functional group compatibility for both alkyl oxalates and vinyl triflates. The...
An electrochemically driven, nickel-catalyzed reductive coupling ofN-hydroxyphthalimide esters with aryl halides is reported. The reaction proceeds under mild conditions in a divided electrochemical cell and employs a tertiary amine as the reductant. This decarboxylative C(sp3)–C(sp2) bond-forming trans...
In this communication, we report the first reductive cross- electrophile coupling of wide range of aryl (pseudo)halides with a malononitrile derivative for a one-step synthesis of benzonitriles (Scheme 1a, bottom arrow). The reaction uses 2- ...
Zhang X, Liu H, Hu X, Tang G, Zhu J, Zhao Y (2011) Ni(II)/Zn catalyzed reductive coupling of aryl halides with diphenylphosphine oxide in water. Org Lett 13:3478-3481Zhang Xinghua,Liu Huizhi,Hu Xiaomei,Tang Guo,Zhu Jun,Zhao Yufen.Ni(II)/Zn catalyzed reductive coupling of aryl ...
by the reduction of Mn, which then proceeds with an enantiodetermining migratory insertion into alkene to forge the intermediateD. Next,Dundergoes the coupling with the alkyl iodide via a SET process to generate the alkyl-Ni(III) speciesF. The six-membered lactams3or5could obtain by reductive...
The flourishing Ni/photoredox-catalyzed asymmetric couplings typically rely on redox-neutral reactions. In this work, we report a reductive cross-coupling of aryl iodides and α-chloroboranes under a dual catalytic regime to further enrich the metallapho
coupling of nickel enables thesyn-cross-dialkylation of alkynes at room temperature. This reductive protocol enables the sequential installation of two different alkyl substituents onto alkynes in a regio- and stereo-selective manner, circumventing the tedious preformation of sensitive organometallic ...