Hao Qu, Xiaobo Yan, Wei Shi, Wangsiyuan Teng, Xiaoqiang Jin, Zhenxuan Shao, Yongxing Zhang, Shenzhi Zhao, Yan Wu*, Zhaoming Ye*, Xiaohua Yu*.Engineered sensory nerve guides self-adaptive bone healing via NGF-TrkA signaling p...
It has been previously shown that ET-1 (Endothelin-1) signaling pathway contributes to an increase in NGF expression, while Cn-NFAT (Calcineurin-Nuclear Factor of Activated T Cells) signaling pathway significantly depresses NGF expression. However, the molecular mechanisms involved in atrial ...
The results from the TrkA blocking group proves that the NGF/TrkA signaling pathway can reduce the expression of growth-associated protein 43 and inhibit the regeneration of nerve axons. The results from the double blocking agent group shows that the interaction of the Nogo-A/NgR signaling ...
This study aimed to test the hypothesis that the NGF-tropomyosin receptor kinase A (TrkA) (high-affinity NGF receptor) pathway plays a role in the calcification process of human articular chondrocytes (hACs). A 14-aa small peptide of NGF (Nsp) previously shown to activate NGF signaling in ...
3. LianXia Formula Granule Attenuates Cardiac Sympathetic Remodeling in Rats with Myocardial Infarction via the NGF/TrKA/PI3K/AKT Signaling Pathway [J] . Sai-Sai Li, Nan Kang, Xiang-Lei Li, Evidence-based complementary and alternative medicine: eCAM . 2021,第a期 机译:Lianxia公式颗粒通过NGF...
However, the authors suggest that this estrogen effect is rather due to lipid catabolism in addition to aging-associated lipid peroxidation, leading to enhanced membrane lipid depletion around the Piezo2 ion channels and not through the cAMP signaling pathway. The negative influence of estrogen on ...
Increased expression of Mcl-1 is responsible for the blockage of TRAIL-induced apoptosis mediated by EGF/ErbB1 signaling pathway. J Cell Biochem 2003; 89: 1177–1192. 47 Liu H, Yang J, Yuan Y, Xia Z, Chen M, Xie L et al. Regulation of Mcl-1 by constitutive activation of NF-κB ...
“neurotrophin receptor trafficking meets signal transduction field” will be to elucidate the traffic control mechanisms governing the directed movement of signaling endosomes. Much is already known on the trafficking of the receptor for epidermal growth factor, EGFR. We will summarize the known traffic...
Such critical participation of p38 MAPK or JNK in the intrinsic pathway of apoptosis is well documented in several other, nonneural contexts, particularly in the heart.37 Con- sistently, the activity of NGF in modulating cellular damage of ischemic heart is remarkable38 and recapitulates the anti...
The results from the TrkA blocking group proves that the NGF/TrkA signaling pathway can reduce the expression of growth-associated protein 43 and inhibit the regeneration of nerve axons. The results from the double blocking agent group shows that the interaction of the Nogo-A/NgR...